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刘子建学术文献,含TTTS(双胎输血综合症)和sIUGR(选择性宫内生长受限)

CURRICULUM VITAE Name: LAU, Tze Kin Fetal Medicine Centre Paramount Clinic Room 409, 4/F Central Building 1 Pedder Street, Central Hong Kong Year of Birth: Sex: 1963 Male

Medical Registration: Hong Kong Medical Council since 1989 General Medical Council (UK) since 1991 General Medical Council Specialist Registration (UK) since 1997 Hong Kong Medical Council (Specialist Registration) since 1998

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EDUCATION AND QUALIFICATIONS Tertiary education: (1982 - 1988): The Chinese University of Hong Kong (Including one year of Potential Medical Major, 2 pre-clinical years and 3 clinical years) Academic Qualifications and Diplomas MBChB The Chinese University of Hong Kong (Jul 1988) M.Med (O&G) The National University of Singapore (Dec 1993) MD The Chinese University of Hong Kong (Dec 1999, with merit) Professional qualifications MRCOG Royal College of Obstetricians and Gynaecologists (1993) MHKCOG Hong Kong College of Obstetricians and Gynaecologists (1993) FHKAM(O&G) The Hong Kong Academy of Medicine (1995) FHKCOG Hong Kong College of Obstetricians and Gynaecologists (2002) FRCOG Royal College of Obstetricians and Gynaecologists (2006) First Fellow in Maternal Fetal Medicine, HKCOG (July 2005)

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POSITIONS HELD Dates Position Institution Fetal Medicine Centre, Paramount Clinic, Hong Kong

CURRENT POSITION Feb 2011 Private Specialists

PAST POSITIONS Feb 2011 – Clinical Professor Department of Obstetrics and Gynaecology, Oct 2011 (Honorary) The Chinese University of Hong Kong, Shatin, Hong Kong 2002-Feb 2011 Professor Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, Hong Kong Oct 1999 Senior Lecturer / Department of Obstetrics and Gynaecology, 2002 Professor The Chinese University of Hong Kong, Shatin, Hong Kong Feb 1994 – Lecturer / Department of Obstetrics and Gynaecology, Sep 1999 Associate Professor The Chinese University of Hong Kong, Shatin, Hong Kong Jun 1992 Medical officer Department of Obstetrics and Gynaecology, Jan 1994 Prince of Wales Hospital, Shatin, Hong Kong Jul 1991 Jun 1992 Jul 1989 Jun 1991 Medical officer Medical officer Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, Hong Kong Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Shatin, Hong Kong

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CURRENT OTHER ACADEMIC APPOINTMENTS 1. 2. 3. 4. 5. 6. 7. School Director, Hong Kong Branch of the Ian Donald Inter-university School of Medical Ultrasound, 2007 - present Academic Editor, PLoS Medicine, January 2009 - present Editorial Board Member, BJOG. Oct 2011- present Editorial Board Member, Ultrasound in Obstetrics and Gynecology, Jan 2008 - present 中华妇产科杂志第十一届编委会委员 (Chinese Journal of Obstetrics and Gynecology). 2010 - present 中国产前诊断杂志副主编。September 2008 – present. International Editorial Review Board, Taiwanese Journal of Obstetrics and Gynecology. Sep 2007 till present

CURRENT SERVICE TO COMMUNITY / PROFESSION: 1. Chairman, The Chinese Fetal Medicine Foundation. Sep 2006 – present. 2. Board Member, The Fetus As A Patient International Society. Mar 2007-present 3. Board Member, International Society of Ultrasound in Obstetrics and Gynecology (ISUOG). Oct 2010 - present 4. 海峡两岸医药卫生交流协会超声医学专家委员会常务委员。2011 年 10 月月。(Cross-straits Medicine Exchange Association). 2014 年 10

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Special clinical skills Expert in the following areas: - Obstetric ultrasonography - Invasive prenatal diagnostic techniques, including amniocentesis, chorionic villus sampling, fetal blood sampling and coelocentesis - Invasive in utero therapy including shunting operation, in utero transfusion and laser therapy for twin-twin transfusion syndrome - Diagnostic and therapeutic fetoscopy Research interests - Various aspects of prenatal diagnosis and therapy especially obstetric ultrasound, twin pregnancy and molecular genetics.

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PUBLICATIONS (refereed and indexed)

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Salomon LJ, Alfirevic Z, Bilardo CM, Chalouhi GE, Ghi T, Kagan KO, Lau TK, Papageorghiou AT, Raine-Fenning NJ, Stirnemann J, Suresh S, Tabor A, Timor-Tritsch IE, Toi A, Yeo G; International Society of Ultrasound in Obstetrics. ISUOG practice guidelines: performance of first-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol 2013 Jan;41(1):102-113. Chen S, Lau TK, Zhang C, Xu C, Xu Z, Hu P, Xu J, Huang H, Pan L, Jiang F, Chen F, Pan X, Xie W, Liu P, Li X, Zhang L, Li S, Li Y, Xu X, Wang W, Wang J, Jiang H, Zhang X. A method for non-invasive detection of fetal large deletions/duplications by low coverage massively parallel sequencing. Prenat Diagn. 2013 Jun;33(6):584-590. Lau TK, Jiang FM, Stevenson RJ, Lo TK, Chan LW, Chan MK, Lo PS, Wang W, Zhang HY, Chen F, Choy KW. Secondary findings from non-invasive prenatal testing for common fetal aneuploidies by whole genome sequencing as a clinical service. Prenat Diagn. 2013 Jun;33(6):602-608. Pan M, Li FT, Li Y, Jiang FM, Li DZ, Lau TK, Liao C. Discordant results between fetal karyotyping and non-invasive prenatal testing by maternal plasma sequencing in a case of uniparental disomy 21 due to trisomic rescue. Prenat Diagn. 2013 Jun;33(6):598-601. Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK. Detection of the fetal conotruncal anomalies using real-time three-dimensional echocardiography with live xPlane imaging of the fetal ductal arch view. Prenat Diagn. 2013 May;33(5):462-466. Choi H, Lau TK, Jiang FM, Chan MK, Zhang HY, Lo PS, Chen F, Zhang L, Wang W. Fetal aneuploidy screening by maternal plasma DNA sequencing: 'False positive' due to confined placental mosaicism. Prenat Diagn. 2013 Feb;33(2):198-200. Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK. Can live xPlane imaging of the in-plane view of interventricular septum be used to detect fetal conotruncal anomalies? J Matern Fetal Neonatal Med 2013 Mar;26(4):373-377. Lau TK, Jiang F, Chan MK, Zhang H, Salome Lo PS, Wang W. Non-invasive prenatal screening of fetal Down syndrome by maternal plasma DNA sequencing in twin pregnancies. J Matern Fetal Neonatal Med. 2013 Mar;26(4):434-437. Yeung SW, Suen SSh, Yu SCh, Lao TT, Leung TY, Lau TK. Spontaneous carotid cavernous fistula complicating pregnancy. Hong Kong Med J. 2013 Jun;19(3):258-261. Dan S, Chen F, Choy KW, Jiang F, Lin J, Xuan Z, Wang W, Chen S, Li X, Jiang H, Leung TY, Lau TK, Su Y, Zhang W, Zhang X. Prenatal detection of aneuploidy and imbalanced chromosomal arrangements by massively parallel sequencing. PLoS One. 2012;7(2):e27835. Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK. A Novel Way to Visualize the Ductal Arch and Aortic Arch by Real-time Three-dimensional Ultrasound with Live xPlane Imaging. Ultrasound Obstet Gynecol. 2012 Mar;39(3):316-321.

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Chen PW, Chen M, Leung TY, Lau TK. Effect of image settings on the measurement of nuchal translucency thickness by semi-automated system. Ultrasound Obstet Gynecol. 2012 Feb;39(2):169-174. Suen SS, Lao TT, Chan OK, Lau TK, Leung TY, Chan PK. Relationship between age and prevalence of hepatitis B infection in first-year university students in Hong Kong. Infection. 2012 Dec 12. [Epub ahead of print] Chung MK, Lao TT, Ting YH, Leung TY, Lau TK, Wong TW. Environmental Factors in the First Trimester and Risk of Oral-Facial Clefts in the Offspring. Reprod Sci. 2012 Dec 26. [Epub ahead of print] Dan S, Wang W, Ren J, Li Y, Hu H, Xu Z, Lau TK, Xie J, Zhao W, Huang H, Xie J, Sun L, Zhang X, Wang W, Liao S, Qiang R, Cao J, Zhang Q, Zhou Y, Zhu H, Zhong M, Guo Y, Lin L, Gao Z, Yao H, Zhang H, Zhao L, Jiang F, Chen F, Jiang H, Li S, Li Y, Wang J, Wang J, Duan T, Su Y, Zhang X. Clinical application of massively parallel sequencingbased prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11??105 pregnancies with mixed risk factors. Prenat Diagn 2012 Dec;32(13):1225-1232. Pan M, Chen M, Sahota DS, Lao TT, Lau TK, Leung TY. Can we use the frontomaxillary facial angle in the first trimester to predict facial cleft? Prenat Diagn. 2012 May;32(5):491493. Ting YH, Lao TT, Law LW, Annie Hui SY, Chor CM, Lau TK, Leung TY. Arabin cerclage pessary in the management of cervical insufficiency. J Matern Fetal Neonatal Med. 2012 Dec;25(12):2693-2695. Lau TK, Chan MK, Lo PS, Chan HY, Chan WK, Koo TY, Ng HY, Pooh RK. Noninvasive prenatal screening of fetal sex chromosomal abnormalities: perspective of pregnant women. J Matern Fetal Neonatal Med. 2012 Dec;25(12):2616-2619. Tong Leung VK, Lao TT, Suen SS, Chan OK, Sahota DS, Lau TK, Leung TY. Breastfeeding initiation: is this influenced by maternal hepatitis B infection? J Matern Fetal Neonatal Med. 2012 Nov;25(11):2390-2394. Xiong Y, Liu T, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK. Comparison of real-time three-dimensional echocardiography and spatiotemporal image correlation in assessment of fetal interventricular septum. J Matern Fetal Neonatal Med. 2012 Nov;25(11):2333-2338. Lau TK, Chan MK, Connie Chan HY, Kim Chan WS, Koo TY, Joyce Ng HY, Pooh RK, Salome Lo PS. Clinical utility of Non-Invasive Fetal Trisomy (NIFTY) test- Early experience. J Matern Fetal Neonatal Med. Oct;25(10):1856-1859. Tong Leung VK, Hung Suen SS, Sahota DS, Lau TK, Leung TY. External cephalic version does not increase the risk of intrauterine death- A 17-year experience and literature review. J Matern Fetal Neonatal Med. 2012 Sep;25(9):1774-1778. Lau TK, Chen F, Pan X, Pooh RK, Jiang F, Li Y, Jiang H, Li X, Chen S, Zhang X. Noninvasive prenatal diagnosis of common fetal chromosomal aneuploidies by maternal plasma DNA sequencing. J Matern Fetal Neonatal Med. 2012 Aug;25(8):1370-1374.

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Sahota DS, Pooh RK, Choy KW, Leung TY, Lau TK. First trimester serum markers stability during sample transportation from the obstetrical site to the screening laboratory. J Matern Fetal Neonatal Med. J Matern Fetal Neonatal Med. 2012 Jul;25(7):966-969. Singh Sahota D, Leung WC, Kee To W, Pan Chan W, Lau TK, Yeung Leung T. Quality assurance of nuchal translucency for prenatal fetal Down syndrome screening. J Matern Fetal Neonatal Med. 2012 Jul;25(7):1039-1043. Suen SS, Khaw KS, Law LW, Sahota DS, Lee SW, Lau TK, Leung TY. The force applied to successfully turn a foetus during reattempts of external cephalic version is substantially reduced when performed under spinal analgesia. J Matern Fetal Neonatal Med. 2012 Jun;25(6):719-722. Chen M, Chen H, Yang X, Wang HF, Leung TY, Sahota DS, Lao TT, Lau TK. Normal range of intracranial translucency (IT) assessed by three-dimensional ultrasound at 11??+??0 to 13??+??6 weeks in a Chinese population. J Matern Fetal Neonatal Med. 2012 May;25(5):489-92. Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK. Scan the fetal heart by real-time three-dimensional echocardiography with live xPlane imaging. J Matern Fetal Neonatal Med. 2012 Apr;25(4):324-8. Pan M, Chen M, Leung TY, Sahota DS, Ting YH, Lau TK. Outcome of monochorionic twin pregnancies with abnormal umbilical artery Doppler between 16 and 20 weeks of gestation. J Matern Fetal Neonatal Med. 2012 Mar;25(3):277-80. Hui SY, Chor CM, Lau TK, Lao TT, Leung TY. Cerclage Pessary for Preventing Preterm Birth in Women with a Singleton Pregnancy and a Short Cervix at 20 to 24 Weeks: A Randomized Controlled Trial. Am J Perinatol. 2012 Aug 8. [Epub ahead of print] Leung VK, Suen SSh, Ting YH, Law LW, Lau TK, Leung TY. Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax. Hong Kong Med J. 2012 Apr;18(2):156-9. Liu XX, Lau TK, Wang HF, Wong SM, Leung TY. [Fetoscopic guided laser occlusion for twin-to-twin transfusion syndrome in 33 cases.] Zhonghua Fu Chan Ke Za Zhi. 2012 Aug;47(8):587-591. [Article in Chinese]. Sun Q, Xu J, Hu SQ, Chen M, Ma RM, Lau TK, Zhang L, Xiao X, Qian Y, Guo Z. [Distribution and normal reference range of fetal nuchal translucency thickness in Kunming pregnant women in the first trimester]. Zhonghua Fu Chan Ke Za Zhi. 2012 Jul;47(7):514517. [Article in Chinese]. Pan M, Choy KW, Liao C, Lau TK. [Combined spectral karyotyping and microarraybased comparative genomic hybridization for the diagnosis of a case with ring chromosome 15]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2012 Oct;29(5):562-565. [Article in Chinese]. Leung KT, Chan KY, Ng PC, Lau TK, Chiu WM, Tsang KS, Li CK, Kong CK, Li K. The tetraspanin CD9 regulates migration, adhesion and homing of human cord blood CD34+ hematopoietic stem and progenitor cells. Blood. 2011 Feb 10;117(6):1840-1850.

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Chiu RW, Akolekar R, Zheng YW, Leung TY, Sun H, Chan KC, Lun FM, Go AT, Lau ET, To WW, Leung WC, Tang RY, Au-Yeung SK, Lam H, Kung YY, Zhang X, van Vugt JM, Minekawa R, Tang MH, Wang J, Oudejans CB, Lau TK, Nicolaides KH, Lo YM. Noninvasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study. BMJ. 2011; 342:c7401. Tsui NB, Kadir RA, Chan KC, Chi C, Mellars G, Tuddenham EG, Leung TY, Lau TK, Chiu RW, Lo YM. Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA. Blood. 2011 Mar 31;117(13):3684-3691. Lun FM, Jin YY, Sun H, Leung TY, Lau TK, Chiu RW, Lo YM. Noninvasive Prenatal Diagnosis of a Case of Down Syndrome due to Robertsonian Translocation by Massively Parallel Sequencing of Maternal Plasma DNA. Clin Chem. 2011 Jun;57(6):917-919. Liao GJ, Lun FM, Zheng YW, Chan KC, Leung TY, Lau TK, Chiu RW, Lo YM. Targeted massively parallel sequencing of maternal plasma DNA permits efficient and unbiased detection of fetal alleles. Clin Chem 2011;57(1):92-101. Chen EZ, Chiu RW, Sun H, Akolekar R, Chan KC, Leung TY, Jiang P, Zheng YW, Lun FM, Chan LY, Jin Y, Go AT, Lau ET, To WW, Leung WC, Tang RY, Au-Yeung SK, Lam H, Kung YY, Zhang X, van Vugt JM, Minekawa R, Tang MH, Wang J, Oudejans CB, Lau TK, Nicolaides KH, Lo YM. Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing. PLoS One. 2011;6(7):e21791. Lee KY, Fong BSP, Tsang KS, Lau TK, Ng PC, Lam AC, Chan KYY, Wang CC, Kung HF, Li CK, Li K. Fetal stromal niches enhance human embryonic stem cell-derived hematopoietic differentiation and globin switch. Stem Cells Devel 2011;20(1):31-38. Fung LW, Lao TT, Suen SS, Chan OK, Lau TK, Ngai KL, Chan PK, Leung TY. Seroprevalence of varicella zoster virus among pregnant women in Hong Kong: Comparison with self-reported history. Vaccine. 2011 Oct 26;29(46):8186-8188. Leung T, Stuart O, Suen S, Sahota D, Lau T, Lao T. Comparison of perinatal outcomes of shoulder dystocia alleviated by different type and sequence of manoeuvres: a retrospective review. BJOG 2011 Jul;118(8):985-990. Leung TY, Stuart O, Sahota DS, Suen SS, Lau TK, Lao TT. Head-to-body delivery interval and risk of fetal acidosis and hypoxic ischaemic encephalopathy in shoulder dystocia: a retrospective review. BJOG. 2011 Mar;118(4):474-479. Leung TY, Vogel I, Lau TK, Chong W, Hyett JA, Petersen OB, Choy KW. Identification of submicroscopic chromosomal aberrations in fetuses with increased nuchal translucency and an apparently normal karyotype. Ultrasound Obstet Gynecol 2011; 38(3): 314-319. Lau TK, Leung TY. Prenatal diagnosis of morbidly adherent placenta. Int J Obstet Anesth. 2011 Apr;20(2):107-109. Hui SY, Chan SC, Lam SY, Lau TK, Chung KH.A prospective study on the prevalence of hydronephrosis in women with pelvic organ prolapse and their outcomes after treatment. Int Urogynecol J. 2011 Dec;22(12):1529-1534.

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Chan OK, Lao TT, Suen SS, Lau TK, Leung TY. Correlation between maternal hepatitis B surface antigen carrier status with social, medical and family factors in an endemic area: have we overlooked something? Infection. 2011 Oct;39(5):419-426. Fung TY, Sahota DS, Lau TK, Leung TY, Chan LW, Chung TK. Placental site in the second trimester of pregnancy and its association with subsequent obstetric outcome. Prenat Diagn. 2011 Jun;31(6):548-554. Chitty LS, Lau TK. First trimester screening – new directions for antenatal care? Prenat Diagn 2011;31(1):1-2. Suen SS, Lao TT, Chan OK, Kou TK, Chan SC, Kim JH, Lau TK, Leung TY. Maternal understanding of commercial cord blood storage for their offspring-a survey among pregnant women in Hong Kong. Acta Obstet Gynecol Scand 2011; 90(9):1005-1009. Chan OK, Lao TT, Suen SS, Lau TK, Leung TY. Knowledge on hepatitis B infection among pregnant women in a high endemicity area. Patient Educ Couns. 2011 Dec;85(3):516-20. Chan LW, Ting YH, Lao TT, Chau MM, Fung TY, Leung TY, Sahota DS, Lau TK. The use of three-dimensional ultrasound does not improve training in fetal biometric measurements. J Matern Fetal Neonatal Med. 2011 Sep;24(9):1173-1175. Sahota DS, Chen M, Leung TY, Chan LW, Fung TY, Ting YH, Lau TK. Assessment of sonographer nuchal translucency measurement performance – central tendency and dispersion. J Matern Fetal Neonatal Med. 2011 Jun;24(6):812-6. Law LW, Sahota DS, Chan LW, Chen M, Lau TK, Leung TY. Serum placental growth factor and fms-like tyrosine kinase 1 during first trimester in Chinese women with preeclampsia - a case-control study. J Matern Fetal Neonatal Med 2011 Jun;24(6):808-11. Ting YH, Lao TT, Lau TK, Chung MK, Leung TY. Isolated absent or hypoplastic nasal bone in the second trimester fetus: is amniocentesis necessary? J Matern Fetal Neonatal Med. 2011 Apr;24(4):555-558. Chen M, Wang HF, Leung TY, Sahota DS, Borenstein M, Nicolaides K, Lao TT, Lau TK. Frontomaxillary facial angle at 11+0 to 13+6 weeks in Chinese population. J Matern Fetal Neonatal Med. 2011 Mar;24(3):498-501. Yang XH, Chen M, Leung TY, Wong SM, Lau TK. Use of three-dimensional (3D) sonography to assess the true midsagittal plane of fetal spine. J Matern Fetal Neonatal Med. 2011 Feb;24(2):297-300. Tong YK, Jin S, Chiu RW, Ding C, Chan KC, Leung TY, Yu L, Lau TK, Lo YM. Noninvasive Prenatal Detection of Trisomy 21 by an Epigenetic-Genetic ChromosomeDosage Approach. Clin Chem 2010; 56(1):90-98. Tsui NB, Akolekar R, Chiu RW, Chow KC, Leung TY, Lau TK, Nicolaides KH, Lo YM. Synergy of Total PLAC4 RNA Concentration and Measurement of the RNA SingleNucleotide Polymorphism Allelic Ratio for the Noninvasive Prenatal Detection of Trisomy 21. Clin Chem 2010; 56(1):73-81.

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Tong YK, Chiu RW, Akolekar R, Leung TY, Lau TK, Nicolaides KH, Lo YM. Epigenetic-genetic chromosome dosage approach for fetal trisomy 21 detection using an autosomal genetic reference marker. PLoS One 2010;5(12):e15244. Tsui DW, Lam YM, Lee WS, Leung TY, Lau TK, Lau ET, Tang MH, Akolekar R, Nicolaides KH, Chiu RW, Lo YM, Chim SS. Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome. PLoS one 2010; 5(11):e15069. Choy KW, To KF, Chan AW, Lau TK, Leung TY. Second-trimester detection of MowatWilson syndrome using comparative genomic hybridization microarray testing. Obstet Gynecol. 2010; 115(2 Pt 2): 462-465. Leung TY, Pooh RK, Wang CC, Lau TK, Choy KW. Classification of pathogenic or benign status of CNVs detected by microarray analysis. Expert Rev Mol Diagn 2010;10(6):717-721. Lao TT, Suen SS, Leung TY, Sahota DS, Lau TK. Universal rubella vaccination programme and maternal rubella immune status: A tale of two systems. Vaccine 2010; 28(10): 2227-2230 Lao TT, Sahota DS, Suen SS, Lau TK, Leung TY. Chronic hepatitis B virus infection and rubella susceptibility in pregnant women. J Viral Hepat. 2010;17(10):737-741. Suen SS, Lao TT, Sahota DS, Lau TK, Leung TY. Implications of the relationship between maternal age and parity with hepatitis B carrier status in high endemicity area. J Viral Hepat.2010;17(5):372-378. Choy KW, Setlur SR, Lee C, Lau TK. The impact of human copy number variation on a new era of genetic testing. BJOG 2010; 117(4): 391-398. Xiong Y, Wah YM, Chan LW, Leung TY, Fung TY, Lau TK. Real-time three-dimensional ultrasound with Live xPlane imaging assists first-trimester acquisition of a true midsagittal section. Ultrasound Obstet Gynecol 2010;36(2):136-140. Xiong Y, Wah YM, Chen M, Fung TY, Leung TY, Lau TK. Assessment of the fetal interventricular septum using real-time three-dimensional echocardiography with Live 3D imaging. Ultrasound Obstet Gynecol 2010;35(6):754-755. Yang X, Chen M, Wang HF, Leung TY, Borenstein M, Nicolaides K, Sahota DS, Lau TK. Learning curve in measurement of fetal frontomaxillary-facial angle at 11(+0) to 13(+6) weeks of gestation. Ultrasound Obstet Gynecol. 2010; 35(5): 530-534. Chan LW, Lau TK. Re: counseling in isolated mild fetal ventriculomegaly. Ultrasound Obstet Gynecol. 2010; 35(5): 624-562 Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK. Comparison of first trimester contingent screening strategies for Down syndrome. Ultrasound Obstet Gynecol 2010; 35(3): 286-291. Fung TY, To KF, Sahota DS, Chan LW, Leung TY, Lau TK. Massive subchorionic thrombohematoma: a series of 10 cases. Acta Obstet Gynecol Scand 2010;89(10):13571361.

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Cheung CW, Leung TY, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK. Outcome of induction of labour using maternal characteristics, ultrasound assessment and biochemical state of the cervix. J Matern Fetal Neonatal Med. 2010;23(12):1406-1412. Law LW, Sahota DS, Chan LW, Chen M, Lau TK, Leung TY. Effect of long-term storage on placental growth factor and fms-like tyrosine kinase 1 measurements in samples from pregnant women. J Matern Fetal Neonatal Med. 2010 Dec;23(12):1475-1480. Law LW, Pang MW, Chung TK, Lao TT, Lee DT, Leung TY, Sahota DS, Lau TK. Randomised trial of assigned mode of delivery after a previous cesarean section - Impact on maternal psychological dynamics. J Matern Fetal Neonatal Med. 2010;23(10):11061113. Chan OK, Sahota DS, Leung TY, Chan LW, Fung TY, Lau TK. Nausea and vomiting in health-related quality of life among Chinese pregnant women. Aust NZJ Obstet Gynaecol. 2010;50(6):512-518. Evans MI, Lau TK. Making decisions when no good choices exist: Delivery of the survivor after intrauterine death of the co-twin in monochorionic twin pregnancies. Fetal Diagn Ther. 2010; 28(4):191-195. Yang X, Leung TY, Kee WD, Chen M, Chan LW, Lau TK. Fetoscopic laser photocoagulation in the management of twin-twin transfusion syndrome: local experience from Hong Kong. Hong Kong Med J 2010;16(4):275-281. Lo YM, Chan KC, Sun H, Chen EZ, Jiang P, Lun FM, Zheng YW, Leung TY, Lau TK, Cantor CR, Chiu RW. Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus. Sci Transl Med 2010; 2(61):61ra91. Xiong Y, Wah YM, Chen M, Leung TY, Lau TK. Real-time three-dimensional echocardiography using a matrix probe with live xPlane imaging of the interventricular septum. Ultrasound Obstet Gynecol 2009; 34(5): 534-537. Law LW, Leung TY, Sahota DS, Chan LW, Fung TY, Lau TK. Which ultrasound or biochemical markers are independent predictors of small-for-gestational age? Ultrasound Obstet Gynecol 2009; 34(3): 283-287. Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chan OK, Lau TK. First-trimester fetal nasal bone length in an ethnic Chinese population. Ultrasound Obstet Gynecol 2009; 34(1):33-37. Chan LW, Fung TY, Leung TY, Sahota DS, Lau TK. Volumetric (3D) imaging reduces inter- and intraobserver variation of fetal biometry measurements. Ultrasound Obstet Gynecol 2009; 33(4): 447-452. Sahota DS, Leung TY, Fung TY, Chan LW, Law LW, Lau TK. Medians and correction factors for biochemical and ultrasound markers in Chinese women undergoing firsttrimester screening for trisomy 21. Ultrasound Obstet Gynecol 2009; 33(4):387-393. Sahota DS, Leung TY, Leung TN, Chan OK, Lau TK. Fetal crown-rump length and estimation of gestational age in an ethnic Chinese population. Ultrasound Obstet Gynecol 2009; 33(2):157-160

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Law LW, Lau TK, Fung TY, Leung TY, Wang CC, Choy KW. De novo 16p13.11 microdeletion identified by high-resolution array CGH in a fetus with increased nuchal translucency. BJOG 2009; 116(2): 339-343. Pang MW, Law LW, Leung TY, Lai PY, Lau TK. Sociodemographic factors and pregnancy events associated with women who declined vaginal birth after cesarean section. Eur J Obstet Gynecol Reprod Biol 2009; 143(1):24-28. Chan YM, Sahota DS, Leung TY, Choy KW, Chan OK, Lau TK. Chinese women's preferences for prenatal diagnostic procedure and their willingness to trade between procedures. Prenat Diagn 2009; 29(13):1270-1276. Chen M, Yang X, Leung TY, Sahota DS, Fung TY, Chan LW, Lao TT, Lau TK. Study on the applicability of frontomaxillary facial angle in the first-trimester trisomy 21 fetuses in Chinese population. Prenat Diagn 2009; 29(12):1141-1144. Tsui NB, Wong BC, Leung TY, Lau TK, Chiu RW, Dennis Lo YM. Non-invasive prenatal detection of fetal trisomy 18 by RNA-SNP allelic ratio analysis using maternal plasma SERPINB2 mRNA: a feasibility study. Prenat Diagn 2009; 29(11):1031-1037. Chan YM, Sahota DS, Chan OK, Leung TY, Lau TK. Miscarriage after invasive prenatal diagnostic procedures: how much risk our pregnant women are willing to take? Prenat Diagn. 2009; 29(9):870-874. Chen M, Wang HF, Leung TY, Fung TY, Chan LW, Sahota DS, Lao TH, Lau TK. First trimester measurements of nasal bone length using three-dimensional ultrasound. Prenat Diagn. 2009; 29(8): 766-770. Pang WW, Tsui MH, Sahota D, Leung TY, Lau TK, Lo YM, Chiu RW. A strategy for identifying circulating placental RNA markers for fetal growth assessment. Prenat Diagn. 2009; 29(5):495-504. Heung MM, Tsui NB, Leung TY, Lau TK, Dennis Lo YM, Chiu RW. Development of extraction protocols to improve the yield for fetal RNA in maternal plasma. Prenat Diagn 2009; 29(3):277-279. Lau ET, Tang L, Wong C, Yung Hang L, Ghosh A, Leung WC, Sin WK, Lau TK, Kung YY, Tang MH. Assessing discrepant findings between QF-PCR on uncultured prenatal samples and karyotyping on long-term culture. Prenat Diagn 2009; 29(2): 151-155 Chen M, Leung TY, Sahota DS, Fung TY, Chan LW, Law LW, Chau MC, Lao TH, Lau TK. Ultrasound screening for fetal structural abnormalities performed by trained midwives in the second trimester in a low-risk population--an appraisal. Acta Obstet Gynecol Scand 2009; 88(6):713-719. Yu YM, Chen M, Xiong Y, Chau MM, Li RS, Lau TK. Comparison of conventional and PureWave Crystal transducer in obstetric sonography. J Matern Fetal Neonatal Med. 2009; 22(7) 616-621.

89.

90.

91.

92.

93.

94.

95.

96.

97.

98.

99.

100. Leung WC, Choi H, Lau WL, Ng LK, Lau ET, Lo FM, Choy KW, Lau TK, Tang MH, Chin R. Monozygotic dichorionic twins heterokaryotypic for duplication chromosome 2q13-q23.3 Fetal Diagn Ther 2009; 25:397-399

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101. Fung TY, Chan LW, Leung TY, Lau TK. Gastroschisis associated with and intraabdominal umbilical vein varix: a report of 2 cases. Fetal Diagn Ther 2009; 25:404-406 102. Lai CY, Cheung HW, Hsi Lao TT, Lau TK, Leung TY. Is the policy of restrictive episiotomy generalisable? A prospective observational study. J Matern Fetal Neonatal Med 2009; 22(12):1116-1121. 103. Choy KW, Chan LW, Tang MH, Ng LK, Leung TY, Lau TK. Prenatal findings and delineation of de novo concurrent partial trisomy 7q(7q31.2 --> qter) and partial monosomy 6q(6q26 --> qter) by high-resolution array CGH. J Matern Fetal Neonatal Med 2009; 22(11):1014-1020. 104. Chen M, Meagher S, Simpson I, Lau TK. Sonographic features of anorectal atresia at 12 week. J Matern Fetal Neonatal Med. 2009; 22(10):931-933. 105. Leung TY, Chan LW, Law LW, Sahota DS, Fung TY, Leung TN, Lau TK. First trimester combined screening for Trisomy 21 in Hong Kong: outcome of the first 10,000 cases. J Matern Fetal Neonatal Med. 2009; 22(4):300-304. 106. Tsui MH, Ip M, Ng PC, Sahota DS, Leung TN, Lau TK. Change in prevalence of group B Streptococcus maternal colonisation in Hong Kong. Hong Kong Med J 2009; 15(6):414419. 107. Chan YM, Sahota DS, Chan OK, Leung TY, Lau TK. A survey of prenatal first-trimester aneuploidy screening among Hong Kong specialist obstetricians. Hong Kong Med J 2009; 15(6):447-451. 108. Heung MM, Jin S, Tsui NB, Ding C, Leung TY, Lau TK, Chiu RW, Lo YM. Placentaderived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood. PLoS One. 2009 Jun 10;4(6):e5858. 109. Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR, Lo YM. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008; 105(51): 20458-20463. 110. Lun FM, Tsui NB, Chan KC, Leung TY, Lau TK, Charoenkwan P, Chow KC, Lo WY, Wanapirak C, Sanguansermsri T, Cantor CR, Chiu RW, Lo YM. Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma. Proc Natl Acad Sci USA 2008; 105(50): 19920-19925. 111. Lun FM, Chiu RW, Chan KC, Leung TY, Lau TK, Lo YM. Microfluidics Digital PCR Reveals a Higher than Expected Fraction of Fetal DNA in Maternal Plasma. Clin Chem. 2008 Oct;54(10):1664-72. 112. Chim SS, Shing TK, Hung EC, Leung TY, Lau TK, Chiu RW, Dennis Lo YM. Detection and Characterization of Placental MicroRNAs in Maternal Plasma. Clin Chem 2008; 54(3): 482-490. 113. Chim SS, Jin S, Lee TY, Lun FM, Lee WS, Chan LY, Jin Y, Yang N, Tong YK, Leung TY, Lau TK, Ding C, Chiu RW, Lo YM. Systematic Search for Placental DNAMethylation Markers on Chromosome 21: Toward a Maternal Plasma-Based Epigenetic Test for Fetal Trisomy 21. Clin Chem 2008; 54: 500-511. Epub 2008 Jan 17.

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114. Suen PM, Zou C, Zhang YA, Lau TK, Chan J, Yao KM, Leung PS. PDZ-domain containing-2 (PDZD2) is a novel factor that affects the growth and differentiation of human fetal pancreatic progenitor cells. Int J Biochem Cell Biol 2008; 40: 789-803. 115. Leung TY, Sahota D, Chan LW, Law LW, Fung TY, Lau TK. Fetal nasal bone status in Chinese women undergoing first-trimester screening for trisomy 21. Am J Obstet Gynecol. 2008 Nov;199(5):521.e1-5. 116. Pang MW, Leung TN, Lau TK, Hang Chung TK. Impact of first childbirth on changes in women's preference for mode of delivery: follow-up of a longitudinal observational study. Birth 2008; 35(2): 121-128. 117. Ngan Kee WD, Khaw KS, Lau TK, Ng FF, Chui K, Ng KL. Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section. Anaesthesia 2008; 63(12): 1319-1326. 118. Wah YM, Chan LW, Leung TY, Fung TY, Lau TK. How true is a 'true' midsagittal section? Ultrasound Obstet Gynecol 2008; 32(7): 855-859. 119. Sahota DS, Kagan KO, Lau TK, Leung TY, Nicolaides KH. Customized birth weight: coefficients and validation of models in a UK population. Ultrasound Obstet Gynecol 2008; 32(7): 884-889. 120. Lau TK, Evans MI. Second-trimester sonographic soft markers: what can we learn from the experience of first-trimester nuchal translucency screening? Ultrasound Obstet Gynecol 2008; 32(2): 123-125. 121. Leung TN, Pang MW, Daljit SS, Leung TY, Poon CF, Wong SM, Lau TK. Fetal biometry in ethnic Chinese: biparietal diameter, head circumference, abdominal circumference and femur length. Ultrasound Obstet Gynecol 2008; 31(3): 321-327. 122. Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Leung TN, Lau TK. Prediction of birth weight by fetal crown-rump length and maternal serum levels of pregnancy-associated plasma protein-A in the first trimester. Ultrasound Obstet Gynecol. 2008; 31: 10-4. 123. Leung TY, Leung TN, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK. Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women. BJOG 2008; 115(12): 1529-1537. 124. Chan LW, Chan OK, Chau MC, Sahota DS, Leung TY, Fung TY, Lau TK. Expectation and knowledge of pregnant women undergoing first and second trimester ultrasound examination in a Chinese population. Prenat Diagn 2008; 28(8): 739-744. 125. Tam WH, Sahota DS, Lau TK, Li CY, Fung TY. Seasonal Variation in Pre-Eclamptic Rate and Its Association with the Ambient Temperature and Humidity in Early Pregnancy. Gynecol Obstet Invest. 2008; 66(1): 22-26 126. Chan SS, Lau AP, To KF, Leung TY, Lau TK, Leung TN. Umbilical cord ulceration causing foetal haemorrhage and stillbirth. Hong Kong Med J 2008; 14(2): 148-151. 127. Chan LW, Sahota DS, Yeung SY, Leung TY, Fung TY, Lau TK, Leung TN. Side-effect and vital sign profile of nifedipine as a tocolytic for preterm labour. Hong Kong Med J 2008; 14(4): 267-272.

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128. Leung WC, Lau ET, Lau WL, Tang R, Wong SF, Lau TK, Tse KT, Wong SF, To WK, Ng LK, Lao TT, Tang MH; Working Group on Prenatal Diagnosis and Counselling, Hospital Authority. Rapid aneuploidy testing (knowing less) versus traditional karyotyping (knowing more) for advanced maternal age: what would be missed, who should decide? Hong Kong Med J 2008; 14(1): 6-13. 129. Lo YM, Tsui NB, Chiu RW, Lau TK, Leung TN, Heung MM, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C. Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat Med 2007; 13: 218-223. Epub 2007 Jan 130. Lo YM, Lun FM, Chan KC, Tsui NB, Chong KC, Lau TK, Leung TY, Zee BC, Cantor CR, Chiu RW. Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci U S A 2007; 104: 13116-13121. Epub 2007 Jul 30. 131. Yang M, Li K, Ng PC, Chuen CK, Lau TK, Cheng YS, Liu YS, Li CK, Yuen PM, James AE, Lee SM, Fok TF. Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis. Stem Cells 2007; 25: 1800-1806. 132. Tong YK, Chiu RW, Leung TY, Ding C, Lau TK, Leung TN, Lo YM. Detection of restriction enzyme digested target DNA by PCR amplification using a stem-loop primer: application to the detection of hypomethylated fetal DNA in maternal plasma. Clin Chem 2007; 53: 1906-1914. Epub 2007 Sep 27. 133. Lun FM, Chiu RW, Leung TY, Leung TN, Lau TK, Lo YM. Epigenetic Analysis of RASSF1A Gene in Cell-Free DNA in Amniotic Fluid. Clin Chem 2007; 53: 796-798. 134. Chow KC, Chiu RW, Tsui NB, Ding C, Lau TK, Leung TN, Lo YM. Mass spectrometric detection of an SNP panel as an internal positive control for fetal DNA analysis in maternal plasma. Clin Chem 2007; 53: 141-142. 135. Wang CC, Yim KW, Poon TCW, Choy KW, Chu CY, Lui WT, Lau TK, Rogers MS, Leung TN. Innate Immune Response by Ficolin Binding in Apoptotic Placenta Is Associated with the Clinical Syndrome of Preeclampsia. Clin Chem 2007; 53: 42-52. 136. Suen PM, Zou C, Zhang YA, Lau TK, Chan J, Yao KM, Leung PS. PDZ-domain containing-2 (PDZD2) is a novel factor that affects the growth and differentiation of human fetal pancreatic progenitor cells. Int J Biochem Cell Biol. 2007 Oct 24; [Epub ahead of print] 137. Chiu RW, Chim SS, Wong IH, Wong CS, Lee WS, To KF, Tong JH, Yuen RK, Shum AS, Chan JK, Chan LY, Yuen JW, Tong YK, Weier JF, Ferlatte C, Leung TN, Lau TK, Lo KW, Lo YM. Hypermethylation of RASSF1A in human and rhesus placentas. Am J Pathol. 2007 Mar;170(3):941-50 138. Szeto CC, To KF, Lai FM, Chow KM, Tam WH, Chung KY, Leung CB, Lui SF, Li PK, Lau TK. Prevalence and Implications of Isolated Microscopic Hematuria in Asymptomatic Chinese Pregnant Women. Nephron Clin Pract 2007; 105: c147-c152.

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139. Ip M, Rainer TH, Lee N, Chan C, Chau SS, Leung W, Leung MF, Tam TK, Antonio GE, Lui G, Lau TK, Hui DS, Fuchs D, Renneberg R, Chan PK. Value of serum procalcitonin, neopterin, and C-reactive protein in differentiating bacterial from viral etiologies in patients presenting with lower respiratory tract infections. Diagn Microbiol Infect Dis 2007; 59: 131-136. Epub 2007 Jul 26. 140. Pang MW, Lee TS, Leung AK, Leung TY, Lau TK, Leung TN. A longitudinal observational study of preference for elective caesarean section among nulliparous Hong Kong Chinese women. BJOG. 2007 May;114(5):623-9. Epub 2007 Mar 13. 141. Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Spencer K, Lau TK. Firsttrimester combined screening for trisomy 21 in a predominantly Chinese population. Ultrasound Obstet Gynecol 2007; 29: 14-17. 142. Tsui DW, Chan KC, Chim SS, Chan LW, Leung TY, Lau TK, Lo YM, Chiu RW. Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia. Prenat Diagn 2007; 27: 1212-1218. 143. Li RH, Tam WH, Ng PC, Mok TS, Tam B, Lau TK. Microphthalmos associated with Dartmouth combination chemotherapy in pregnancy: a case report. J Reprod Med 2007; 52: 575-576. 144. Leung TN, Leung TY, Chan PK, Fung TY, Lau TK. Fetal parvovirus B19 infection in a twin pregnancy with 1 twin presenting with hydrops fetalis and the other asymptomatic: a case report. J Reprod Med. 2007; 52: 419-421. 145. Wang CC, Chu KO, Chong WS, Li WY, Pang CP, Shum AS, Lau TK, Rogers MS. Tea epigallocatechin-3-gallate increases 8-isoprostane level and induces caudal regression in developing rat embryos. Free Radic Biol Med 2007; 43: 519-527. 146. Chan LW, Leung TY, Leung TN, Fung TY, Lau TK. Foetal intracranial teratoma: choosing the best time and mode of delivery. Hong Kong Med J 2007; 13: 323-326. 147. Pang SM, Leung DT, Leung TY, Lai CY, Lau TK, Chung TKH. Determinants of preference for elective caesarean section in Hong Kong Chinese pregnant women. Hong Kong Med J 2007; 13: 100-105. 148. Tsui MH, Pang MW, Melender HL, Xu L, Lau TK, Leung TN. Maternal fear associated with pregnancy and childbirth in Hong Kong Chinese women. Women Health. 2006;44(4):79-92. 149. Chan KC, Ding C, Gerovassili A, Yeung SW, Chiu RW, Leung TN, Lau TK, Chim SS, Chung GT, Nicolaides KH, Lo YM. Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis. Clin Chem 2006; 52: 2211-2218. 150. Tong YK, Ding C, Chiu RW, Gerovassili A, Chim SS, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo YM. Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: theoretical and empirical considerations. Clin Chem 2006; 52: 2194-2202. 151. Siu SS, Chan MT, Lau TK. Placental Transfer of Ondansetron during Early Human Pregnancy. Clin Pharmacokinet 2006; 45: 419-423.

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152. Choy KW, Wang CC, Ogura A, Lau TK, Rogers MS, Ikeo K, Gojobori T, Lam DS, Pang CP. Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. Physiol Genomics 2006; 25: 9-15. 153. Chan LY, Lau TK. Effect of rosiglitazone on embryonic growth and morphology: a study using a whole rat embryo culture model. Fertil Steril 2006; 86: 490-492. 154. Siu SS, Choy MY, Leung TN, Lau TK. Lack of site-specific production of decidual alpha2 macroglobulin in human pregnancy. J Soc Gynecol Investig 2006; 13: 491-496. 155. Chu CY, Xiao X, Zhou XG, Lau TK, Rogers MS, Fok TF, Law LK, Pang CP, Wang CC. Metablolomic and bioinformatics analyses in asphyxiated neonates. Clin Biochem 2006;39:203-209. 156. Choy KW, Wang CC, Ogura A, Lau TK, Rogers MS, Ikeo K, Gojobori T, Tang LY, Lam DS, Chung TK, Pang CP. Molecular characterization of the developmental gene in eyes: Through data-mining on integrated transcriptome databases. Clin Biochem 2006; 39: 224230. 157. Fok WY, Chan LY, Wong JT, Yu CM, Lau TK. Left ventricular diastolic function during normal pregnancy: assessment by spectral tissue Doppler imaging. Ultrasound Obstet Gynecol 2006; 28: 789-793. 158. Fok WY, Chan LY, Lau TK. The influence of fetal position on amniotic fluid index and single deepest pocket. Ultrasound Obstet Gynecol 2006; 28:162-165. 159. Leung TY, Fok WY, Chan LW, Law LW, Lau TK. Prediction of intrapartum Cesarean delivery for non-reassuring fetal status after a successful external cephalic version by a low pre-version pulsatility index of the fetal middle cerebral artery. Ultrasound Obstet Gynecol 2006; 27: 416-419. 160. Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Lau TK. First-trimester maternal serum levels of placental hormones are independent predictors of second-trimester fetal growth parameters. Ultrasound Obstet Gynecol. 2006; 27: 156-161. 161. Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Lau TK. First-trimester maternal serum level of pregnancy-associated plasma protein-A is an independent predictor of fetal maxillary bone length. Ultrasound Obstet Gynecol 2006; 27: 9-12. 162. Chan LW, Lau TK, Chung TK. Fetal anaemia as a cause of fetal injury: diagnosis and management. Curr Opin Obstet Gynecol 2006; 18: 100-105. 163. Chan YM, Leung TN, Leung TY, Fung TY, Chan LW, Lau TK. The utility assessment of Chinese pregnant women towards the birth of a baby with Down syndrome compared to a procedure-related miscarriage. Prenat Diagn 2006; 26: 819-824. 164. Kong CW, Leung TN, Leung TY, Chan LW, Sahota DS, Fung TY, Lau TK. Risk factors for procedure-related fetal losses after mid-trimester genetic amniocentesis. Prenat Diagn 2006 Oct;26(10):925-930. 165. Leung TY, Sahota DS, Chan LW, Fok WY, Law LW, Lau TK. Variation of force applied during external cephalic version with different patients' characteristic and outcome of version. Acta Obstet Gynecol Scand 2006; 85: 182-187.

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166. Leung TY, Spencer K, Leung TN, Fung TY, Lau TK. Higher median levels of free betahCG and PAPP-A in the first trimester of pregnancy in a Chinese ethnic group. Implication for first trimester combined screening for Down's syndrome in the Chinese population. Fetal Diagn Ther 2006; 21: 140-143. 167. Chan LY, Fok WY, Sahota D, Lau TK. Cord blood thyroid-stimulating hormone level and risk of acidosis at birth. Eur J Obstet Gynecol Reprod Biol 2006; 124: 173-177. 168. Fok WY, Siu SS, Lau TK. Sexual dysfunction after a first trimester induced abortion in a Chinese population. Eur J Obstet Gynecol Reprod Biol 2006; 126: 255-258. 169. Fok WY, Chan LY, Tsui MH, Leung TN, Lau TK, Chung TK. When to induce labor for post-term? A study of induction at 41 weeks versus 42 weeks. Eur J Obstet Gynecol Reprod Biol 2006; 125: 206-210. 170. Yung PB, Chan LY, Lau TK. Re: Reasons for requesting pregnancy termination and attitude of women when request is being refused: A face-to-face interview study. Aust N Z J Obstet Gynaecol 2006; 46: 68-69. 171. Chan LY, Lau TK, Fung TM, Chow KM. Re: Effects of rosiglitazone on hormonal profile and ovulatory function in Chinese women with polycystic ovary syndrome. Aust N Z J Obstet Gynaecol 2006; 46: 170-171. 172. Fung TY, Chan DL, Leung TN, Leung TY, Lau TK. Dextrocardia in pregnancy: 20 years' experience. J Reprod Med 2006; 51: 573-573. 173. Wong TY, Lam WW, Lau TK. Foetal magnetic resonance imaging. Hong Kong Med J 2006; 12: 486-487. 174. Ngan Kee WD, Lee BB, Fung NG, Lau TK, Wong ELY, Khaw KS. Randomised doubleblind comparison of obstetric outcome after epidural labour analgesia using Ropivacaine or Bupivacain. Hong Kong Med J 2006; 12 (S1): 45-47 175. Chim SS, Tong YK, Chiu RW, Lau TK, Leung TN, Chan LY, Oudejans CB, Ding C, Lo YM. Detection of the placental epigenetic signature of the maspin gene in maternal plasma. Proc Natl Acad Sci U S A 2005; 102: 14753-14758 176. Chan KC, Hui AB, Wong N, Lau TK, Leung TN, Lo KW, Lo YM. Investigation of the Genomic Representation of Plasma DNA in Pregnant Women by Comparative Genomic Hybridization Analysis: A Feasibility Study. Clin Chem 2005; 51: 2398-2401. 177. Tsui NB, Chiu RW, Ding C, El-Sheikhah A, Leung TN, Lau TK, Nicolaides KH, Lo YM. Detection of Trisomy 21 by Quantitative Mass Spectrometric Analysis of SingleNucleotide Polymorphisms. Clin Chem 2005; 51: 2358-2362. 178. Chiu RW, Lui WB, El-Sheikhah A, Chan AT, Lau TK, Nicolaides KH, Lo YM. Comparison of protocols for extracting circulating DNA and RNA from maternal plasma. Clin Chem 2005; 51: 2209-2210. 179. Wong BC, Chiu RW, Tsui NB, Chan KC, Chan LW, Lau TK, Leung TN, Lo YM. Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: implications for noninvasive prenatal diagnosis and monitoring. Clin Chem 2005; 51: 1786-1795.

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180. Rogers MS, Wang CC, Lau TK, Xiao X, Zhou XG, Fok TF, Chu KO, Pang CP. Relationship between Isoprostane Concentrations, Metabolic Acidosis, and Morbid Neonatal Outcome. Clin Chem 2005;51: 1271-1274. 181. Chung GT, Chiu RW, Chan KC, Lau TK, Leung TN, Chan LW, Lo YM. Detrimental effect of formaldehyde on plasma RNA detection. Clin Chem 2005; 51: 1074-1076. 182. Chung GT, Chiu RW, Chan KC, Lau TK, Leung TN, Lo YM. Lack of dramatic enrichment of fetal DNA in maternal plasma by formaldehyde treatment. Clin Chem 2005; 51: 655-658. 183. Chan LY, Fok WY, Wong JT, Yu CM, Leung TN, Lau TK. Reference charts of gestationspecific tissue Doppler imaging indices of systolic and diastolic functions in the normal fetal heart. Am Heart J 2005; 150: 750-755. 184. Chong WS, Kwan PC, Chan LY, Chiu PY, Cheung TK, Lau TK. Expression of divalent metal transporter 1 (DMT1) isoforms in first trimester human placenta and embryonic tissues. Hum Reprod 2005; 20: 3532-3538. 185. Chan LY, Yeung JH, Lau TK. Placental transfer of rosiglitazone in the first trimester of human pregnancy. Fertil Steril 2005; 83: 955-958. 186. Siu SS, Yeung JH, Pang MW, Chiu PY, Lau TK. Placental transfer of Zidovudine in first trimester of pregnancy. Obstet Gynecol 2005; 106: 824-827. 187. Liu BY, Wang CC, Lau TK, Chu CY, Pang CP, Rogers MS, Leung TN. Meconiumstained liquor during labor is associated with raised neonatal cord blood 8-isoprostaglandin F2alpha concentration. Am J Obstet Gynecol 2005; 192: 289-294. 188. Leung PL, Hui DS, Leung TN, Yuen PM, Lau TK. Sleep disturbances in Chinese pregnant women. BJOG 2005; 112: 1568-1571. 189. Lau TK, Yu SC, Leung TY, To KF, Fung TY, Leung TN. Prenatal embolisation of a large chorioangioma using enbucrilate. BJOG 2005; 112: 1002-1004. 190. Leung TN, Pang MW, Leung TY, Poon CF, Wong SM, Lau TK. Cervical length at 18-22 weeks of gestation for prediction of spontaneous preterm delivery in Hong Kong Chinese women. Ultrasound Obstet Gynecol 2005; 26: 713-717. 191. Fung TY, Leung TN, Leung TY, Lau TK. Fetal intra-abdominal umbilical vein varix: what is the clinical significance? Ultrasound Obstet Gynecol 2005; 25: 149-154. 192. Chan LW, Chau MC, Leung TY, Fung TY, Leung TN, Lau TK. Expectation and knowledge of women undergoing first-trimester combined screening for Down syndrome in a Chinese population. Prenat Diagn 2005; 25: 1248-1252. 193. Lau TK, Leung TN. Genetic screening and diagnosis. Curr Opin Obstet Gynecol 2005; 17: 163-169. 194. Leung TN, Lau TK, Chung TKH. Thalassaemia screening in pregnancy. Curr Opin Obstet Gynecol 2005; 17: 129-134.

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195. Lau TK, Pang MW, Sahota DS, Leung TN. Impact of hypertensive disorders of pregnancy at term on infant birth weight. Acta Obstet Gynecol Scand 2005; 84:875-877. 196. Chan LY, Lam KY, Metreweli C, Lau TK. Duplex ultrasound screening for deep vein thrombosis in Chinese after cesarean section. Acta Obstet Gynecol Scand 2005; 84: 368370 197. Fok WY, Chan LW, Leung TY, Lau TK. Maternal experience of pain during external cephalic version at term. Acta Obstet Gynecol Scand 2005; 84: 748-751. 198. Fok WY, Leung TY, Tsui MH, Leung TN, Lau TK. Fetal hemodynamic changes after amniotomy. Acta Obstet Gynecol Scand 2005; 84: 166-169. 199. Lee CH, Lau TK, To KF, Lam HS, Chan AW, Ng PC. Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis. Acta Paediatr. 2005; 94: 1843-1847. 200. Lam MH, Chan LY, Wong SF, Tam W, Lau TK. Relationship between maternal pelvic parameters and idiopathic term breech presentation. Eur J Obstet Gynecol Reprod Biol 2005; 118: 267-268. 201. Lau TK, Leung TY, Fung TY, Chan LW, Sahota DS, Leung TN. Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients. Chin Med J 2005;118:1675-1681. 202. Fok WY, Leung TY, Tsui MH, Leung TN, Lau TK. Effect of prostaglandin E2 for cervical priming on fetal hemodynamics. J Reprod Med 2005; 50: 697-700. 203. Ding C, Chiu RW, Lau TK, Leung TN, Chan LC, Chan AY, Charoenkwan P, Ng IS, Law HY, Ma ES, Xu X, Wanapirak C, Sanguansermsri T, Liao C, Ai MA, Chui DH, Cantor CR, Lo YM. MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis. Proc Natl Acad Sci USA 2004; 101: 1076210767. 204. Choy MY, Leung TN, Leung PS, Lau TK. Effect of hypoxia on urocortin production in human gestational trophoblasts in vitro. Am J Reprod Immunol 2004; 52: 118-1123. 205. Tsui NB, Chim SS, Chiu RW, Lau TK, Ng EK, Leung TN, Tong YK, Chan KC, Lo YM. Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling. J Med Genet 2004; 41: 461-467. 206. Ng EK, El-Sheikhah A, Chiu RW, Chan KC, Hogg M, Bindra R, Leung TN, Lau TK, Nicolaides KH, Lo YM. Evaluation of Human Chorionic Gonadotropin beta-Subunit mRNA Concentrations in Maternal Serum in Aneuploid Pregnancies: A Feasibility Study. Clin Chem. 2004; 50: 1055-1057. 207. Chan KCA, Zhang J, Hui ABY, Wong N, Lau TK, Leung TN, Lo KW, Huang DWS, and Lo YMD. Size Distributions of Maternal and Fetal DNA in Maternal Plasma. Clin Chem 2004; 50: 88-92. 208. Choy MY, Siu SS, Leung TN, Lau TK. Human decidual production of hepatocyte-growth factor is not influenced by trophoblastic invasion in vivo. Fertil Steril 2004; 82 Suppl 3: 1220-1225.

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209. Chan LY, Tang JL, Tsoi KF, Fok WY, Chan LW, Lau TK. Intrapartum cesarean delivery after successful external cephalic version: a meta-analysis. Obstet Gynecol 2004; 104: 155160. 210. Tsui MH, Ngan Kee WD, Ng FF, Lau TK. A double blinded randomised placebocontrolled study of intramuscular pethidine for pain relief in the first stage of labour. BJOG 2004; 111: 648-655. 211. Leung TY, Lok IH, Tam WH, Leung TN, Lau TK. Deterioration in cord blood gas status during the second stage of labour is more rapid in the second twin than in the first twin. BJOG 2004; 111: 546-9. 212. Leung TY, Sahota DS, Fok WY, Chan LW, Lau TK. External cephalic version induced fetal cerebral and umbilical blood flow changes are related to the amount of pressure exerted. BJOG 2004; 111: 430-435. 213. Lee BB, Ngan Kee WD, Ng FF, Lau TK, Wong EL. Epidural infusions of ropivacaine and bupivacaine for labor analgesia: a randomized, double-blind study of obstetric outcome. Anesth Analg 2004; 98: 1145-1152. 214. Chan LY, Chiu PY, Lau TK. Embryotoxicity study of ginsenoside Rc and Re in in vitro rat whole embryo culture. Reprod Toxicol 2004; 19: 131-134. 215. Chan LY, Chiu PY, Lau TK. Hydrosalpinx fluid induced embryotoxicity and lipid peroxidation. Reprod Toxicol. 2004; 19:147-148. 216. Leung TN, Ching Chau MM, Chang JJ, Leung TY, Fung TY, Lau TK. Attitudes towards termination of pregnancy among Hong Kong Chinese women attending prenatal diagnosis counselling clinic. Prenat Diagn. 2004; 24: 546-551. 217. Chan LY, Leung TY, Fok WY, Chan LW, Lau TK. Prediction of successful vaginal delivery in women undergoing external cephalic version at term for breech presentation. Eur J Obstet Gynecol Reprod Biol. 2004; 116: 39-42. 218. Chan LY, Fu L, Leung TN, Wong SF, Lau TK. Obstetric outcomes after cervical ripening by multiple doses of vaginal prostaglandin E2. Acta Obstet Gynecol Scand 2004; 83: 7074. 219. Lam PM, Leung TN, Ng PC, Vlantis AC, Wong W, Lau TK. Congenital cervical fibrosacroma with hydrops fetalis. Acta Obstet Gynecol Scand. 2004; 83: 773-776. 220. Chan LY, Leung TY, Fok WY, Chan LW, Lau TK. Cord blood acid-base status at delivery after successful external cephalic version. Acta Obstet Gynecol Scand 2004; 83: 436-439. 221. Lam PM, Lo KW, Lau TK. Unsuccessful medical treatment of cesarean scar ectopic pregnancy with systematic Methotrexate - a report of two cases. Acta Obstet Gynecol Scand 2004; 83: 108-111. 222. Choy MY, Leung TN, Lau TK. Corticotropin-releasing hormone peptide and human firsttrimester placental growth. Early Hum Dev 2004; 79: 77-80. 223. Lau TK, Leung TY, Fung TY, Leung TN. Treatment of twin-twin transfusion syndrome by fetoscopic laser photocoagulation. Chin Med J (Engl) 2004; 117: 1431-1434.

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224. Pang MW, Leung TN, Lau TK. A validation study of ultrasonic foetal weight estimation models for Hong Kong Chinese singleton pregnancies. Hong Kong Med J. 2004; 10: 384388. 225. Ng EK, Tsui NB, Lau TK, Leung TN, Chiu RW, Panesar NS, Lit LC, Chan KW, Lo YM. From the Cover: mRNA of placental origin is readily detectable in maternal plasma. Proc Natl Acad Sci USA 2003; 100: 4748-4753. 226. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003; 18:2166-2168. 227. Chan LY, Chiu PY, Cheung LP, Haines CJ, Tung HF, Lau TK. A study of teratogenicity of hydrosalpinx fluid using a whole rat embryo culture model. Hum Reprod 2003; 18: 955958. 228. Ng EK, Leung TN, Tsui NB, Lau TK, Panesar NS, Chiu RW, Lo YM. The Concentration of Circulating Corticotropin-releasing Hormone mRNA in Maternal Plasma Is Increased in Preeclampsia. Clin Chem 2003; 49: 727-731. 229. Chan LY, Leung TN, Chan KC, Tai HL, Lau TK, Wong EM, Lo YM. Serial analysis of fetal DNA concentrations in maternal plasma in late pregnancy. Clin Chem 2003; 49: 678680 230. Lam PM, Lo KW, Yu MM, Lau TK, Cheung TH. Intravenous leiomyomatosis with atypical histologic features: A case report. Int J Gynecol Cancer 2003;13: 83-87 231. Lau TK, Leung TY, Yu SC, To KF, Leung TN. Prenatal treatment of chorioangioma by microcoil embolisation. BJOG 2003; 110: 70-73. 232. Pang MW, Leung TN, Sahota DS, Lau TK, Chang AM. Customizing fetal biometric charts. Ultrasound Obstet Gynecol. 2003 Sep;22(3):271-6. 233. Leung TY, Sahota DS, Fok WY, Chan LW, Lau TK. Quantification of contact surface pressure exerted during external cephalic version. Acta Obstet Gynecol Scand 2003; 82: 1017-1022. 234. Chan LY, Chiu PY, Lau TK. Cord blood thyroid-stimulating hormone level in twin pregnancy. Acta Obstet Gynecol Scand 2003; 82: 28-31. 235. Leung TN, Lam PM, Ng PC, Lau TK. Repeated courses of antenatal corticosteroids: Is it justified? Acta Obstet Gynecol Scand. 2003; 82: 589-596. 236. Chan LY, Chiu PY, Lau TK. Cord blood thyroid-stimulating hormone level in high-risk pregnancies. Eur J Obstet Gynecol Reprod Biol. 2003; 108: 142-145. 237. Chan LY, Lam MH, Lau TK, Chin RK. Successful treatment of recurrent, intractable hyperemesis gravidarum with methylprednisolone. A case report. J Reprod Med 2003; 48: 293-295. 238. Choy MY, Leung TN, Leung PS, Lau TK. First trimester human trophoblast production of placental corticotrophin-releasing hormone (CRH) is unresponsive to hypoxia in-vitro. Early pregnancy 2003; VI: 235-247

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239. Lau TW, Leung TN, Chan LYS, Lau TK, Chan KCA, Tam WH, Lo YMD. Fetal DNA clearance from maternal plasma is impaired in preeclampsia. Clin Chem 2002; 48: 21412146 240. Qin Y, Lau TK, Rogers MS. Second-trimester ultrasonographic assessment of the umbilical coiling index. Ultrasound Obstet Gynecol 2002; 20: 458-63 241. Chan LY, Chiu PY, Siu NS, Wang CC, Lau TK. Diclofenac-induced embryotoxicity is associated with increased embryonic 8-isoprostaglandin F2alpha level in rat whole embryo culture. Reprod Toxicol 2002; 16:841-844. 242. Chiu RWK, Lau TK, Leung TN, Chow KCK, Chiu DHK, Lo YMD. Prenatal exclusion of ? thalassaemia major by examination of maternal plasma Lancet 2002: 360;998-1000. 243. Chan LYS, Leung TY, Fok WY, Chan LW, Lau TK. High incidence of obstetric interventions after successful external cephalic version. BJOG 2002; 109: 627-631. 244. Chiu RWK, Lau TK, Cheung PT, Gong ZQ, Leung TN, Lo DYM. Noninvasive Prenatal Exclusion of Congenital Adrenal Hyperplasia by Maternal Plasma Analysis: A Feasibility Study. Clin Chem 2002; 48: 778-780. 245. Poon LLM, Leung TN, Lau TK, Chow KCK, Lo YMD. Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma. Clin Chem 2002; 48: 35-41 246. SSN Siu, JHK Yeung, TK Lau. An in-vivo study on placental transfer of naproxen in early human pregnancy. Hum Reprod 2002; 17: 1056-1059 247. Leung TY, Tam WH, Leung TN, Lok IH, Lau TK. Effect of twin-to-twin delivery interval on umbilical cord blood gas in the second twins. BJOG 2002; 109: 63-67 248. Chan YL, Lam WWM, Lau TK, Metreweli C, Chan DPN. Back pain in pregnancy – magnetic resonance imaging correlation. Clinical Radiology. 2002; 57: 1109-1112. 249. Chan LY, Yuen PM, Lo WK, Lau TK. Symptomatic venous thromboembolism in Chinese patients after gynecologic surgery: incidence and disease pattern. Acta Obstet Gynecol Scand 2002; 81: 343-6 250. Siu SSN, Yip SK, Cheung CW, Lau TK. Treatment of intractable hyperemesis gravidarum by ondansetron. Eur J Obstet Cynecol Reprod Bio 2002; 105:73-74 251. Chan LY, Chiu PY, Siu SSN, Lau TK. A study of diclofenac-induced teratogenicity during organogenesis using a whole rat embryo culture model. Human Reprod 2001; 16: 23902393. 252. Leung PS, Tsai SJ, Wallukat G, Leung TN, Lau TK. The upregulation of angiotensin II receptor AT(1) in human preeclamptic placenta. Mol Cell Endocrinol 2001; 184: 95-102. 253. Chung TK, Lau TK, Yip AS, Chiu HF, Lee DT. Antepartum Depressive Symptomatology Is Associated With Adverse Obstetric and Neonatal Outcomes. Psychosom Med 2001; 63: 830-834.

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254. Chiu RWK, Poon LLM, Lau TK, Leung TN, Wong EMC, Lo YMD. Effects of bloodprocessing protocols on fetal and total DNA quantification in maternal plasma. Clin Chem 2001; 47: 1607-1613. 255. Chan LY, Chiu PY, Lau TK. A study of Hypericin-induced teratogenicity during organogenesis using a whole rate embryo culture model. Fertil Steril 2001; 76:1073-1074 256. Chan LYS, Lau TK, Chiu PY, Wong GWK, Leung TN. Levels of cord Blood thyroid stimulating hormone after external cephalic version. BJOG 2001; 108: 1076-1080. 257. Tam WH, Rogers MS, Lau TK, Arumanayagam M. The predictive value of serum 1,5anhydro-D-glucitol in pregnancies at increased risk of gestational diabetes mellitus and gestational impaired glucose tolerance. BJOG 2001; 108: 754-756 258. Leung TN, Zhang J, Lau TK, Chan LY, Lo YMD. Increased maternal plasma fetal DNA concentrations in women who eventually develop preeclampsia. Clin Chem 2001; 47: 137139 259. Ngan Kee WD, Lau TK, Khaw KS, Lee BB. Comparison of metaraminol and ephedrine infusions for maintaning arterial pressure during spinal anesthesia for elective cesarean section. Anesthesiology 2001; 95: 307-313 260. Chan LY, Tam WH, Lau TK. Venous thromboembolism in pregnant Chinese women. Obstet Gynecol 2001; 98: 471-475 261. Poon LL, Leung TN, Lau TK, Lo YM. Circulating fetal RNA in maternal plasma. Ann NY Acad Sci 2001; 945:207-10 262. Lau TK, Leung TN, Leung TY, Pang MW, Tam WH. Fetal scalp cysts: challenge in diagnosis and counseling. J Ultras Med 2001; 20: 175-177 263. Siu SSN, Leung TN, Leung TY, Ng SW, Yeung CK, Lau TK. Prenatal Diagnosis of intraabdominal mature testicular teratoma. J Ultrasound Med 2001; 20:1257-1260. 264. Chan LY, Leung TN, Lau TK. Influences of perinatal factors on cord blood thyroidstimulating hormone level. Acta Obstet Gynecol Scand 2001; 80: 1014-1018. 265. Leung TY, Chan LW, Tam WH, Leung TN, Lau TK. Risk and prediction of preterm delivery in pregnancies complicated by antepartum hemorrhage of unknown origin before 34 weeks. Gynecol Obstet Invest 2001;52(4):227-231. 266. Lau TK, Leung TN, Leung TY, Pang SMW, Tam WH. Rare major maternal complications after second trimester amniocentesis: sequelae of avoiding a transplacental approach. Aust NZ J Obstet Gynaecol 2001; 41: 472-273. 267. Lam PM, Yuen PM, Lau TK, Leung TN. Relationship between birthweight and repeated courses of antenatal corticosteroids. Aust NZ J Obstet Gynaecol 2001;41:281-284 268. Chan LY, Lau TK, Wong SF, Yuen PM. Pyometra: What is its clinical significance? J Reprod Med 2001; 46:952-956. 269. Lo KWK, Lau TK. Intracardiac leiomyomatosis. Case report and literature review. Arch Gynecol Obstet. 2001; 264: 209-210

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270. Poon LLM, Leung TN, Lau TK, Lo YMD. Prenatal detection of fetal Down’s syndrome from maternal plasma. Lancet 2000; 356; 1819-1820 271. Siu SSN, Yeung JHK, Lau TK. A study on placental transfer of diclofenac in first trimester of human pregnancy. Human Reprod 2000; 15: 2423-2425 272. Poon LLM, Leung TN, Lau TK, Lo YMD. Presence of fetal RNA in maternal plasma. Clin Chem 2000; 46: 1832-1834. 273. Ngan Kee WD, Khaw KS, Lee BB, Lau TK, Gin T. A dose-response study of prophylactic intravenous ephedrine for the prevention of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg 2000; 90: 1390-1395 274. Qin Y, Wang CC, Lau TK, Rogers MS. Color ultrasonography: a useful technique in the identification of nuchal cord during labor. Ultra Obstet Gynecol 2000; 15: 413-417. 275. Lau TK, Lo KWK, Chan LYS, Leung TY, Lo YMD. Cell-free fetal deoxyribonucleic acid in maternal circulation as a marker of fetal-maternal hemorrhage in patients undergoing external cephalic version near term. Am J Obstet Gynecol 2000; 183: 712-716 276. Lo YMD, Lau TK, Chan LYS, Leung TN, Chang AMZ. Quantitative Analysis of the Bidirectional Fetomaternal Transfer of Nucleated Cells and Plasma DNA. Clin Chem 2000; 46: 1301-1309 277. Lau TK, Leung TY, Lo KWK, Fok WY, Rogers MS. Effect of external cephalic version at term on fetal circulation. Am J Obstet Gynecol 2000; 182: 1239-1242 278. Lau TK, Lo KWK, Leung TY, Fok WY, Rogers MS. Outcome of labour after successful external cephalic version at term complicated by isolated transient fetal bradycardia. BJOG 2000;107:401-405 279. Tam WH, Rogers MS, Yip SK, Lau TK, Leung TY. Which screening test is the best for gestational impaired glucose tolerance and gestational diabetes mellitus? Diabetes Care 2000; 23: 1432 280. Wong W, Tang NLS, Lau TK, Wong TW. A new recommendation for maternal weight gain in Chinese women. J Am Diet Assoc 2000; 100: 791-796 281. Leung TY, Lau TK, Lo KWK, Rogers MS. A survey of pregnant women’s attitude towards breech delivery and external cephalic version. Aust NZ J Obstet Gynaecol 2000; 40: 253-259. 282. Pang MW, Leung TN, Sahota DS, Lau TK, Chang AMZ. Development of a customised birthweight standard for ethnic Chinese subjects. Aust NZ J Obstet Gynaecol 2000; 40: 161-164 283. Tang NLS, Leung TN, Zhang J, Lau TK, LoYMD. Detection of fetal-derived paternallyinherited X-chromosome polymorphisms in maternal plasma. Clin Chem 1999;45:20332035 284. Lo YMD, Lau TK, Zhang J, Leung TN, Chang AMZ, Hjelm NM, Elmes RS, Bianchi DW. Increased fetal DNA in the plasma of pregnant women carrying fetuses with trisomy 21. Clin Chem 1999;45:1747-1751

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285. Li JKY, Yeung VTF, Chow CC, Ko GTC, Lau TK, Cockram CS. Hyperemesis gravidarum, transient hyperthyroxinaemia and primary hyperparathyroidism in a Chinese woman. Aust NZ J Med 1999;29:379-380 286. Lo YMD, Zhang J, Leung TN, Lau TK, Chang AMZ, Hjelm NM. Rapid clearance of fetal DNA from maternal plasma. Am J Hum Genet 1999; 64: 218-224 287. Lo YMD, Leung TN, Tein MSC, Sargent IL, Zhang J, Lau TK, Haines CJ, Redman CWG. Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin Chem 1999; 45: 184-188 288. Fung TY, Lau TK, Li CK, Li CK. Homozygous alpha-Thalassemia associated with hypospadias in three survivors. Am J Med Genet 1999; 82: 225-227. 289. Hin LY, Lau TK, Rogers MS, Chang AMZ. Dichotomization of continuous measurements using generalized additive modelling – application in predicting intrapartum caesarean section. Stat Med 1999; 18: 1101-1110 290. Rogers MS, Arumanayagam M, Fung H, Lau TK. Diurnal variation in excretion of Nacetyl-beta-glucosaminidase during pregnancy: implication for the prediction of preeclampsia. Gynecol Obstet Invest 1999; 47: 9-12 291. Chung TKH, Sahota DS, Lau TK, Mongelli JM, Spencer JAD, Haines CJ. Threatened abortion: Prediction of viability based on signs and symptoms. Aust NZ J Obstet Gynaecol 1999; 39: 443-447. 292. Law LK, Lau TK, Fung TY, Rogers MS, Hjelm M. Maternal serum screening for Down syndrome in a teaching hospital in Hong Kong. Chin Med J 1999;112:754-757 293. Leung TN, Zhang J, Lau TK, Hjelm NM, Lo YMD. Maternal plasma fetal DNA as a marker for preterm labour. Lancet 1998; 352: 1904-1905. 294. Yim SF, Lau TK, Sahota DS, Chung TKH, Chang AMZ, Haines CJ. Prospective randomized study of the effect of ‘add-back’ hormone replacement on vascular function during treatment with gonadotropin-releasing hormone agonists. Circulation 1998; 98: 1631-1635. 295. Lo YMD, Tein MSC, Lau TK, Haines CJ, Leung TN, Poon PMK, Wainscoat JS, Johnson PJ, Chang AMZ, Hjelm NM. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for non-invasive prenatal diagnosis. Am J Hum Genet 1998; 62: 768775 296. Lau TK, Fung HYM, Rogers MS, Cheung KL. Racial variation in incidence of Trisomy 21: A survey of 57,742 Chinese deliveries. Am J Med Genet 1998; 75: 386-388 297. Chan YL, Lam WWM, Lau TK, Wong SP, Li CY, Metreweli C. Cervical assessment by magnetic resonance imaging - its relationship with gestational age and interval to delivery. Br J Radiol 1998; 71: 155-159

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298. Lau TK, Wan D, Yim SF, Sanderson JE, Haines CJ. Prospective randomized controlled study of the effect of hormone replacement therapy on peripheral blood flow velocity in postmenopausal women. Fertil Steril 1998; 70: 284-288. 299. Fung TY, Lau TK. Poor perinatal outcome associated with vasa previa : is it preventable? A report of 3 cases and review of the literature. Ultra Obstet Gynecol 1998; 12: 430-433. 300. Fung TY, Lau TK, Yam MC, To KF. Prenatal diagnosis of cardiac osteoma: a case report. Prenat Diag 1998; 18: 1209-1211 301. Fung TY, Lau TK, Tam WH, Li CK. In utero exchange transfusion in homozygous alphathalassemia : a case report. Prenat Diag 1998; 18: 838-841 302. Lau TK, Leung CMY, Li CY. A study of the use of radiological pelvimetry in a Chinese population. Acta Obstet Gynecol Scand 1998; 77: 41-44 303. Lau TK, Fung TY, Wong YF, Fung HYM. A study of fetal sex determination in coelomic fluid. Gynecol Obstet Inv 1998; 45: 16-18 304. Roach VJ, Fung H, Cockram CS, Lau TK, Rogers MS. Evaluation of glucose intolerance in pregnancy using biochemical markers of fetal hyperinsulinaemia. Gynecol Obstet Inv 1998; 45: 174-176 305. Lo KWK, Lau TK. Cushing’s syndrome in pregnancy secondary to adrenal adenoma: A case report and literature review. Gynecol Obstet Inv 1998; 45: 209-212 306. Lau TK, Leung TN. Repeat instrumental delivery: How high is the risk. Aust NZ J Obstet Gynaecol 1998; 38: 31-33 307. Roach VJ, Lau TK, Ngan Kee WD, Wormald PJ. Perioperative documentation: are we doing enough? Aust NZ J Obstet Gynaecol 1998; 38: 166-169. 308. Leung TN, Roach VJ, Lau TK. Incidence of preterm delivery in Hong Kong Chinese. Aust NZ J Obstet Gynaecol 1998;38:138-141. 309. Roach VJ, Lau TK, Wilson D, Rogers MS. The incidence of gestational diabetes in multiple pregnancy. Aust NZ J Obstet Gynaecol 1998; 38: 56-57. 310. Chung THK, Lau TK, Cheung LP, Haines CJ. Compliance with hormone replacement therapy in Chinese women in Hong Kong. Maturitas 1998; 28: 213-219 311. Leung TN, Lau TK, Roach V, Wilson D, Rogers MS, Chang AMZ. Obstetric outcome of illegal immigrants from mainland China in Hong Kong. Int J Gynecol Obstet 1998;62:223227. 312. Lau TK, Lo WK, Rogers M. Pregnancy outcome after successful external cephalic version for breech presentation at term. Am J Obstet Gynecol 1997; 176: 218-223. 313. Lau TK, Lo KWK, Wan D, Rogers MS. Predictors of successful external cephalic version at term: a prospective study. Br J Obstet Gynaecol 1997; 104: 798-802

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314. Lau TK, Fung YM, Fung TY. Fetal diaphragmatic hernia presented with transient unilateral pleural effusion. Ultra Obstet Gynecol 1997; 9: 125-127. 315. Lau TK, Chung TKH, Haines CJ. A preliminary study on the effect of hormone replacement therapy on peripheral flow velocity in postmenopausal women. Maturitas 1997; 26: 53-56. 316. Lau TK, Lo KWK, Wan D, Rogers MS. The implementation of external cephalic version at term for singleton breech presentation - how can we further increase its impact? Aust NZ J Obstet Gynaecol 1997; 37: 393-396 317. Lau TK, Fung HYM, Fung TY. Fetal bowel dilataion - Report of 3 cases with different perinatal outcomes. Aust NZ J Obstet Gynaecol 1997; 37: 323-324 318. Roach VJ, Lau TK, Ngan Kee WD. The quality of citations in major international obstetrics and gynecology journals. Am J Obstet Gynecol 1997; 177: 973-975 319. Hin LY, Lau TK, Rogers M, Chang AMZ. Antepartum and intrapartum prediction of cesarean need: Risk scoring in singleton pregnancies. Obstet Gynecol 1997; 90: 183-186. 320. Yip SK, Lau TK, Rogers MS. A study on prophylactic antibiotics in cesarean section - is it worthwhile? Acta Obstet Gynecol Scand 1997; 76: 547-549 321. Fung TY, Fung HYM, Lau TK, Chang AMZ. Abdomino-amniotic shunting in isolated fetal ascites with polyhydramnios. Acta Obstet Gynecol Scand 1997; 76: 706-707. 322. Tam WH, Fung HYM, Fung TY, Lau TK, To KF. Intra-uterine growth retardation and transverse lie due to massive subchorionic thrombohematoma and overlying large subchorionic cyst. Acta Obstet Gynecol Scand 1997; 76: 381-383. 323. Haines CJ, Chung TKH, Lau TK. Sonographic measurement of endometrial thickness as a predictor of vaginal bleeding in women using continuous combined hormone replacement therpay. Gynecol Obstet Inves 1997; 44: 187-190 324. Ngan Kee WD, Roach VJ, Lau TK. How accurate are references in The Australian and New Zealand Journal of Surgery? Aust NZ J Surg 1997; 67: 417-419 325. Lau WC, Fung HYM, Lau TK, To KF. A benign polypoid adenomyoma: an unusual cause of persistent fetal transverse lie. Eur J Obstet Cynecol Reprod Bio 1997; 74: 23-25 326. Ngan Kee WD, Hung VYS, Roach VJ, Lau TK. A survey of factors influencing patients’ choice of anaesthesia for Caesarean section. Aust NZ J Obstet Gynaecol 1997; 37: 300-303 327. Lo KWK, Lau TK. The use of gonadotropin-releasing hormone analogues in gynaecology. Chin Med J 1997; 110: 746-749

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328. Lo KWK, Lau TK. Ectopic pregnancy in uterosacral ligament. J Obstet Gynaecol Res 1997; 23: 415-419 329. Ngan Kee WD, Roach VJ, Lau TK. The accuracy of references in the Hong Kong Medical Journal. Hong Kong Med J. 1997; 3: 377-380 330. Lau TK, Chung TKH, Haines CJ, Chang AMZ. Fetal sex as a risk factor for fetal distress leading to abdominal delivery. Aust NZ J Obstet Gynaecol 1996; 36: 146-149. 331. Lau TK, Wong SH, Li CY. A study of patient’s acceptance towards vaginal birth after Caesarean section. Aust NZ J Obstet Gynaecol 1996; 36: 155-158. 332. Rogers MS, Lau TK, Wang CC, Yu KM. Amnioinfusion for the prevention of meconium aspiration during labour. Aust NZ J Obstet Gynaecol 1996; 36: 407-410. 333. Chung T, Neale E, Lau TK, Rogers M. A randomized, double blind, controlled trial of tocolysis to assist external cephalic version in late pregnancy. Acta Obstet Gynecol Scand 1996; 75: 720-724. 334. Lau TK, Stock A, Rogers M. Fetomaternal haemorrhage after external cephalic version at term. Aust NZ J Obstet Gynaecol 1995; 35: 173-174. 335. Lau TK, Li CY. A perinatal audit of stillbirths in a teaching hospital in Hong Kong. Aust NZ J Obstet Gynaecol 1994; 34: 416-421. 336. Lau TK, Wong FWS. Uterine leiomyosarcoma associated with pregnancy: report of two cases. Gynecol Oncol 1994; 53: 245-247. 337. Lau TK, Wong FWS. Lymphatic vaginal fistula after Wertheim-Taussig hysterectomy: a case report. Gynecol Oncol 1994; 52: 411-412. 338. Lau TK, Chan F. Unknown uterine scars - unknown risks. Aust NZ J Obstet Gynaecol 1994; 34: 216-217.

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PUBLICATIONS (refereed but non-indexed)

1. 陈 敏 , 胡 芷 洋 , 刘 子 建 . 胎 儿 生 长 受 限 的 诊 断 和 处 理 [J]. 中 国 实 用 妇 科 与 产 科 杂 志,2011,27(4):105-108. 2. 刘子建,梁德杨,陈敏等. 唐氏综合征的产前筛查模式和临床应用 [J]. 中华妇产科杂志, 2010, 45 (6) . 3. 刘子建,梁德杨,陈敏等. 唐氏综合征的产前诊断 [J]. 中华妇产科杂志, 2010, 45 (10) . 4. 陈敏,刘子建. APCMFM 与香港中文大学母胎医学的发展 [J]. 中国产前诊断杂志(电子 版), 2010, 02 (4) . 5. Sahota DS, Leung TY, Lau TK. Determination of individual preferences: why, how and alternatives. Fetal and Maternal Medicine Review 2009;20:301-317 6. Lau TK, Leung TY. Non-invasive prenatal diagnosis: From dream to reality. J Paediat Obstet Gynaecol 2009; 35: 15-131. 7. Lau TK, Leung TY. Prenatal screening and diagnosis of fetal chromosomal abnormalities – Dilemma between best evidence-based model and practicability. Fetal and Maternal Medicine Review 2009; 20: 161-177. 8. Choy KW, Tsang PT, Leung TY, Wang CC, Lau TK. The application of microarray based comparative genomic hybridization in prenatal diagnosis. Fetal Matern Med Rev 2008;19:119-133. 9. 乔宠、刘子建、Jani J、Deprest J。先天性膈疝的产前诊断及宮内治疗进展。中华妇产 科杂志, 2007, 42 (8). CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2007, Vol.42, Issue 8: 563-566 10. 王慧芳,刘子建。双胎输血综合征的判断和临床处理。中国实用妇科与产科杂志; 2007; Vol. 23 (5): 347-351. 11. Kong CW, Lau TK. Common twin-specific complications. J Paediact Obstet Gynaecol 2007; 33: 125-131 12. Leung TY, Lau TK. Prediction of outcome of external cephalic version for breech presentation at term. Fetal and Maternal Medicine Review 2005; 16:245-262. 13. Yam MC, Leung TY, Lau TK, Sung RYT. A fetus with hydropic change secondary to fetal supraventricular tachycardia. HK J Paediatr 2003; 8: 130-132. 14. Lau TK, Poon CF, Wong SM, Chau MCM, Leung TY, Leung TN. The development of a midwife-based obstetric ultrasound service in a teaching hospital. HKJGOM 2001; 2: 68-72 15. Poon CF, Wong SM, Ng SC, Chau MCM, Leung TY, Leung TN, Lau TK. A 2-year audit of a midwife-based obstetric ultrasound service. HKJGOM 2001; 2: 73-79 16. Lau TK, Chau MCM, Leung TY, Pang MWS, Fung TY, Leung TN. Outcome of 555

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consecutive transabdominal chorionic villus samplings in a teaching hospital. HKJGOM 2000; 1: 21-27 17. Lau TK, Wong YF, Chang AMZ. Clinical trial. Chin J Prac Gynecol Obstet 2000; 16: 313314 18. Ng PS, Leung TY, Leung TN, Lau TK. In utero treatment of hydrops fetalis due to parvovirus B19 infection: a case report. HKJGOM 2000; 67-70 19. Lau TK, Wong FWS. Microinvasive carcinoma of the uterine cervix: management and a review of literature. J H K Med Assn. 1993; 45: 53-56. 20. Lau TK, Leung AKL. Endometrial Ablation - Conservative surgery for the treatment of menorrhagia. H K Pract 1991; 13: 1737-1741. 21. Lau TK, Leung AKL. Hysteroscopy - A 1990 update. H K Pract 1991; 13: 1433-1436.

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CHAPTERS, BOOKS etc Chang AMZ, Lau TK. Operative vaginal delivery. In: Turnbull’s Obstetrics, 3rd Edition. Edited by: Chamberlain G, Steer P. Churchill Livingstone, London, 2001. pp581-600. Lau TK. Prenatal fetal surveillance. In: High Risk Pregnancy: Management Options, 4th Edition. Edited by: James DK, Steer PH, Weiner CP, Gonik B. Saunders, Dec 2010, pp163-172.

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INVITED LECTURES 1. 产前分子诊断的新进展。上海围产医学会第二季度学术活动暨 2013 上海围产研讨会会 议。中國上海,2013 年 6 月 29 日。 2. 超声对 FGR 的评估。第三届中国胎儿医学大会。中国产前诊断杂志(电子版)。中国 广州,2013 年 6 月 14-16 日。 3. 无创性胎儿非整倍体产前筛查(NIPT)在产前筛查诊断体系中的地位。中国产前诊断 杂志(电子版)。中国广州,2013 年 6 月 14-16 日。 4. 出生缺陷干预工程的未来发展。苏州市产前筛查和产前诊断技术培训班。苏州市妇幼 保健所。中国苏州,2013 年 6 月 9 日。 5. Thick NT and cystic hygroma: is karytoyping enough? Workshop: Practical guide to prenatal diagnosis. Department of Obstetrics and Gynaecology, The Chinese Univeristy of Hong Kong. Shenzhen. 2 June 2013. 6. Improving your CVS sampling. Department of Obstetrics and Gynaecology, The Chinese Univeristy of Hong Kong. Shenzhen. 2 June 2013. 7. Prenatal diagnosis of achondroplasia. Clinical Genetic Symposium Series S3. Dwarfism: from prenatal diagnosis to postnatal treatment. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Hong Kong. 25 May 2013. 8. Prenatal diagnosis of osteogenesis imperfecta. Clinical Genetic Symposium Series S3. Dwarfism: from prenatal diagnosis to postnatal treatment. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Hong Kong. 25 May 2013. 9. Sonographic assessment of multiple pregnancies. 2013 Cross-Strait Medicine Communication and Cooperation Conference. 5th Cross-Strait Tri-Regional Ultrasound in Medicine Summit Forum. Nanjing, China. 17-18th May 2013. 10. Prenatal diagnosis. 婦產科醫師協會 2013 年會暨婦產科最新進展研討會。澳門婦產科醫 師協會。澳門。2013 年 4 月 28 日。 11. 双胎染色体异常的筛查、诊断及处理。复杂性双胎问题产前超声诊断及宫内治疗研讨 会。深圳市医学继续教育中心。2013 年 3 月 23-25 日。 12. TTTS 及 s-IUGR 的宫内处理方案的选择,围手术期并发症,预后及监测要点。复杂性 双胎问题产前超声诊断及宫内治疗研讨会。深圳市医学继续教育中心。2013 年 3 月 23 -25 日。

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13. 复杂性双胎产前超声监测及管理。复杂性双胎问题产前超声诊断及宫内治疗研讨会。 深圳市医学继续教育中心。2013 年 3 月 23-25 日。 14. USG of abnormalities of fetal lower jaw. Clinical Genetics Symposium Series S2. Facial Dysmorphism: Prenatal USG meets Postnatal Genetics. Depart of Obstetrics and Gynaecology, the Chinese University of Hong Kong. 23-24 March 2013. 15. USG of fetal microcephaly. Clinical Genetics Symposium Series S2. Facial Dysmorphism: Prenatal USG meets Postnatal Genetics. Depart of Obstetrics and Gynaecology, the Chinese University of Hong Kong. 23-24 March 2013. 16. USG of cystic hygroma and prenasal edema. Clinical Genetics Symposium Series S2. Facial Dysmorphism: Prenatal USG meets Postnatal Genetics. Depart of Obstetrics and Gynaecology, the Chinese University of Hong Kong. 23-24 March 2013. 17. Prenatal and pre-pregnancy screening and diagnosis of genetic diseases. Advances in diagnostic molecular pathology and molecular genetics. Hong Kong Molecular Pathology Diagnostic Centre. Hong Kong. 14th January, 2013. 18. 关于这个培訓班及中华胎儿医学基金会产科超声资格认证。产科超声医师资格认证理 论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 19. 超声如何作为一项诊断和筛查工具。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 20. 超声预测胎儿孕龄及评估胎儿生长发育,宫内发育迟缓。产科超声医师资格认证理论 课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 21. 羊水,胎盘,水腫胎兒。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 22. 中孕期超声标记物。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 23. 对异常胎儿的进一步研究、病人的咨询及胎儿宫内治疗。产科超声医师资格认证理论 课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 24. 双胎输血综合征的超声诊断和治疗。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 25. 双胎之一无心畸形的超声诊断和宫内治疗。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。

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26. 胎儿消化系统和前腹壁的正常和异常超声解剖。产科超声医师资格认证理论课程培训 班, 2013 年 1 月 10-13 日, 中国鄭州。 27. 产前超声的常规, 标准和建议。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10 -13 日, 中国鄭州。 28. 产科超声资格认证:培训和建议。产科超声医师资格认证理论课程培训班, 2013 年 1 月 10-13 日, 中国鄭州。 29. 胎儿医学——过去,现在,将来。面向 2013 年母胎生物信息医学与胎儿医学:挑战与 机遇。广州医学院第三附属医院。广州,中国。2012 年 12 月 22 日—23 日。 30. 胎儿宫内治疗: 是否太热了。面向 2013 年母胎生物信息医学与胎儿医学:挑战与机 遇。广州医学院第三附属医院。广州,中国。2012 年 12 月 22 日—23 日。 31. 早孕胎儿心脏畸形。中国首届胎儿心脏畸形与新生儿先心病超声诊断提高班。武汉大 学人民医院。武汉,中国。2012 年 12 月 7 日—9 日。 32. Integrating Molecular Genetic Technologies into Clinical Practice: Perspective from a Clinician. The 7th International Conference on Genomics & Bio-IT APAC 2012. Hong Kong. 29th Nov – 1st Dec 2012. 33. 母胎医学新进展。母胎医学基础与临床研讨班,苏州市立医院。苏州,中国。2012 年 11 月 24 日—25 日。 34. 胎儿非整倍体的无创产前诊断现状。母胎医学基础与临床研讨班,苏州市立医院。苏 州,中国。2012 年 11 月 24 日—25 日。 35. Update on Prenatal Diagnosis。第三届粤港澳检验医学学术大会。香港。2012 年 11 月 9 日—10 日。 36. Abnormal maternal serum markers analytes: Are they useful in predicting pregnancy outcomes? Reversing the Pyramid of Antenatal Care Education Seminar 2012. Kuala Lumpur, Malaysia. 2021 October 2012. 37. The trouble with multiples: Beware. Reversing the Pyramid of Antenatal Care Education Seminar 2012. Kuala Lumpur, Malaysia. 20-21 October 2012. 38. Non-invasive testing: Latest development in fetal cells and cell-free fetal DNA in maternal blood. Reversing the Pyramid of Antenatal Care Education Seminar 2012. Kuala Lumpur, Malaysia. 2021 October 2012. 39. Management of twin complications. 10th Asia Federation of Societies for Ultrasound in Medicine and Biology (AFSUMB) Workshop. Hong Kong. 11th-12th, August, 2012.

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40. New advances in fetal echocardiography and volume imaging. 10th Asia Federation of Societies for Ultrasound in Medicine and Biology (AFSUMB) Workshop. Hong Kong. 11th-12th, August, 2012. 41. 双胎妊娠并发症超声诊断及预后。胎儿出生缺陷产前超声诊断高级课程,国际妇产超 声学会(ISUOG)授权教育课程。北京,中國。2012 年 8 月 3 日—5 日。 42. 单绒毛膜双胎选择性 IUGR 的诊断和治疗。胎儿出生缺陷产前超声诊断高级课程,国 际妇产超声学会(ISUOG)授权教育课程。北京,中國。2012 年 8 月 3 日—5 日。 43. USG diagnosis and assessment of complications of twins. Certificate in Obstetric & Midwifery Ultrasound. The Chinese University of Hong Kong. Hong Kong. 14st April, 2012. 44. Skeletal anomalies. Certificate in Obstetric & Midwifery Ultrasound. The Chinese University of Hong Kong. Hong Kong. 14st April, 2012. 45. 非侵入性产前诊断技术应用于非整倍体异常。第二届中国胎儿医学大会。Beijing,中 國。2012 年 6 月 15-17 日。 46. 双胎染色体异常的筛查、诊断及处理。复杂性双胎问题产前超声诊断及宫内治疗研讨 会。深圳,中国。2012 年 3 月 16-18 日。 47. MC、DC 双胎之一宫内死亡的预后和处理原则。复杂性双胎问题产前超声诊断及宫内 治疗研讨会。深圳,中国。2012 年 3 月 16-18 日。 48. TTTS 及 s-IUGR 的宫内处理方案的选择,围手术期并发症,预后及监测要点。复杂性 双胎问题产前超声诊断及宫内治疗研讨会。深圳,中国。2012 年 3 月 16-18 日。 49. 双胎之一无心畸形的产前超声诊断和临床处理原则。复杂性双胎问题产前超声诊断及 宫内治疗研讨会。深圳,中国。2012 年 3 月 16-18 日。 50. 复杂性双胎产前超声监测及管理。粤港澳复杂性双胎问题产前超声诊断及宫内治疗研 讨会。复杂性双胎问题产前超声诊断及宫内治疗研讨会。深圳,中国。2012 年 3 月 16-18 日。 51. Introduction of FTS. 5th Japan Ian Donald Advanced Seminar 2012, Beppu, Kyushu, Japan. 21-22 January 2012 52. Quality assessment of NT certified examiners. 5th Japan Ian Donald Advanced Seminar 2012, Beppu, Kyushu, Japan. 21-22 January 2012 53. Non-invasive prenatal diagnosis. 5th Japan Ian Donald Advanced Seminar 2012, Beppu, Kyushu, Japan. 21-22 January 2012 54. Non-invasive fetal trisomy test. Adventist Hospital, Hong Kong. 18th October 2011.

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55. Non-invasive fetal trisomy test. Baptist Hospital, Hong Kong. 11th October 2011. 56. Ultrasound education in China. 13th Japan Ian Donald Ultrasound Course. Osaka, Japan. 810th October 2011. 57. Non-invasive test for aneuploidy. 13th Japan Ian Donald Ultrasound Course. Osaka, Japan. 810th October 2011. 58. Livescan – First trimester scan. 13th Japan Ian Donald Ultrasound Course. Osaka, Japan. 810th October 2011. 59. The updated review and new development of prenatal screening strategies for fetal aneuploidy. The 1st Chinese Congress of Fetal Medicine. Shanghai, China. 8-11th September 2011. 60. Achieving excellence in the first trimester screening. The 1st Chinese Congress of Fetal Medicine. Shanghai, China. 8-11th September 2011. 61. What is next after non-invasive prenatal diagnosis has been put into practice? 11th Perinatal Symposium 2011. The Perinatal Chapter of Hong Kong. 3rd September 2011. 62. Recent Advances in Prenatal Screening and Diagnosis. Hong Kong Institute of Medical Laboratory Sciences. Hong Kong. 24th August 2011. 63. 三维/四维超声:妇产超声新技术概论。妇产超声前沿技术:3D/4D 的应用进展。中山 大学第一附属医院。2011 年八月 20-21 日。 64. 国际妇产超声学会及其教育课程简介。妇产超声前沿技术:3D/4D 的应用进展。中山 大学第一附属医院。2011 年八月 20-21 日。 65. Microcephaly and macrocephaly. Ian Donald Seminar on Fetal Neurology. Hong Kong. 1314 August 2011 66. Non-invasive prenatal diagnosis. Union Hospital, Hong Kong. 12st July 2011 67. Selective IUGR in twin pregnancy. Hong Kong Baptist Hospital, Hong Kong. 14th June 2011 68. Quality control and monitoring of performance. 2nd FOCUS in O&G, 2nd OGSHK Annual Scientific Meeting, 50th Anniversary OGSHK. Hong Kong. 11-12 June 2011. 69. Fetal reduction. Postgraduate study day, University of Hong Kong, Hong Kong. 7th June 2011 70. Sonographic assessment of complicated monochorionic twin pregnancies. 2nd Mindray Ultrasound Forum. Shenzhen, China. 29 May – 2 June 2011. 71. First trimester screening: Introduction and overview. Advanced ultrasound course on first trimester screening. Mongolian Federation of Obstetricians and Gynecologists, Telemedicine

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Support for Maternal and Newborn Health, The Chinese Fetal Medicine Foundation. Ulaanbaatar, Mongolia. 21-23 May, 2011. 72. Amniocentesis and CVS / Karyotyping / Rapid karyotyping / aCGH. Advanced ultrasound course on first trimester screening. Mongolian Federation of Obstetricians and Gynecologists, Telemedicine Support for Maternal and Newborn Health, The Chinese Fetal Medicine Foundation. Ulaanbaatar, Mongolia. 21-23 May, 2011. 73. Assessment of background risk risk assessment by NT thickness / How to measure NT. Advanced ultrasound course on first trimester screening. Mongolian Federation of Obstetricians and Gynecologists, Telemedicine Support for Maternal and Newborn Health, The Chinese Fetal Medicine Foundation. Ulaanbaatar, Mongolia. 21-23 May, 2011. 74. First trimester serum screening and first trimester combined screening. Advanced ultrasound course on first trimester screening. Mongolian Federation of Obstetricians and Gynecologists, Telemedicine Support for Maternal and Newborn Health, The Chinese Fetal Medicine Foundation. Ulaanbaatar, Mongolia. 21-23 May, 2011. 75. Certification / recertification / audit of first trimester screening. Advanced ultrasound course on first trimester screening. Mongolian Federation of Obstetricians and Gynecologists, Telemedicine Support for Maternal and Newborn Health, The Chinese Fetal Medicine Foundation. Ulaanbaatar, Mongolia. 21-23 May, 2011. 76. 宫内治疗。第三届围产医学新进展高峰论坛。中国重庆。2011 年 4 月 2 1 - 23 日。 77. 中孕标志物。11-14 周产科超声检查培训。中国上海。2011 年 4 月 2 - 4 日。 78. 早孕筛查的质控。11-14 周产科超声检查培训。中国上海。2011 年 4 月 2 - 4 日。 79. 早孕筛查: 计算软件的选择,认证。11-14 周产科超声检查培训。中国上海。2011 年 4 月 2 - 4 日。 80. Selective IUGR in twin pregnancy. Hong Kong Sanatorium & Hospital, Hong Kong. 17 Mar 2011. 81. 11-14 孕周一站式胎儿染色体畸形筛查。深港胎儿畸形早期产前筛查新进展研讨会。深 圳市第二人民医院超声科和香港中文大学威尔斯亲王医院母胎医学中心。深圳,中 国。2011 年 2 月 19 日。 82. 11-14 孕周胎儿染色体畸形介入检查。深港胎儿畸形早期产前筛查新进展研讨会。深圳 市第二人民医院超声科和香港中文大学威尔斯亲王医院母胎医学中心。深圳,中国。 2011 年 2 月 19 日。 83. Selective fetal reduction. Commissioned training in Obstetrics and Gynaecology, Hospital Authority of Hong Kong. 2 March 2011.
th

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84. Local experience of endoscopic laser therapy for TTTS. 7th International Scientific Meeting, ISUOG. 25-27 February 2011. Macau SAR, Chain. 85. live 3D in fetal cardiac exam. 7th International Scientific Meeting, ISUOG. 25-27 February 2011. Macau SAR, Chain. 86. Routine anomalies scan by midwives. 7th International Scientific Meeting, ISUOG. 25-27 February 2011. Macau SAR, Chain. 87. Introduction of first trimester screening. Japan Ian Donald Advanced Seminar 2011. Sapporo, Hokkaido, Japan. 29-30 January 2011. 88. Quality assessment of NT certified examiners. Japan Ian Donald Advanced Seminar 2011. Sapporo, Hokkaido, Japan. 29-30 January 2011. 89. Non-invasive prenatal diagnosis. Japan Ian Donald Advanced Seminar 2011. Sapporo, Hokkaido, Japan. 29-30 January 2011. 90. Screening for Chromosomal Anomalies by First Trimester Biochemical and Ultrasound Markers. 9th Asia pacific Congress on Human Genetics. Hong Kong. 30 Nov – 3 Dec 2010. 91. 双胎及复杂性双胎总论:流行病学及胚胎学。粤港澳复杂性双胎问题产前超声诊断及 宫内治疗研讨会。深圳,中国。2010 年 11 月 27-28 日。 92. 双胎染色体异常的筛查、诊断及处理。粤港澳复杂性双胎问题产前超声诊断及宫内治 疗研讨会。深圳,中国。2010 年 11 月 27-28 日。 93. MC、DC 双胎之一宫内死亡的预后和处理原则。粤港澳复杂性双胎问题产前超声诊断 及宫内治疗研讨会。深圳,中国。2010 年 11 月 27-28 日。 94. TTTS 和单绒毛膜双胎中选择性宫内生长受限(s-IUGR)的产前超声诊断及鉴别诊断。粤 港澳复杂性双胎问题产前超声诊断及宫内治疗研讨会。深圳,中国。2010 年 11 月 2728 日。 95. TTTS 及 s-IUGR 的宫内处理方案的选择,围手术期并发症,预后及监测要点。粤港澳 复杂性双胎问题产前超声诊断及宫内治疗研讨会。深圳,中国。2010 年 11 月 27-28 日。 96. 双胎之一无心畸形的产前超声诊断和临床处理原则。粤港澳复杂性双胎问题产前超声 诊断及宫内治疗研讨会。深圳,中国。2010 年 11 月 27-28 日。 97. 复杂性双胎产前超声监测及管理。粤港澳复杂性双胎问题产前超声诊断及宫内治疗研 讨会。深圳,中国。2010 年 11 月 27-28 日。 98. Advances in prenatal diagnosis. 1st AMM-AMS-HKAM Tripartite Congress / 44th MalaysiaSingapore Congress of Medicine. Hong Kong. 12-14 November 2010.

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99. Application of aCGH in the prenatal and postnatal assessment of neurological anomalies. 6th International Academy of Perinatal Medicine Meeting, International Symposium on Fetal Neurology. Osaka, Japan. 22-24 October 2010. 100.Fetal cells and fetal DNA in maternal blood: Past, present and future. 20th World Congress on Ultrasound in Obstetrics and Gynecology. Prague, Czech Republic. 10-14 October 2010. 101.Invasive and non-invasive diagnosis of chromosomal abnormalities. 20th World Congress on Ultrasound in Obstetrics and Gynecology. Prague, Czech Republic. 10-14 October 2010. 102.Live 3D in prenatal diagnosis. Australasian Society for Ultrasound in Medicine 40th Annual Congress. Gold Coast, Brisbane, Australia. 24-26 September 2010. 103.Increased nuchal translucency but normal karyotyping: What elase? Australasian Society for Ultrasound in Medicine 40th Annual Congress. Gold Coast, Brisbane, Australia. 24-26 September 2010. 104.First trimester markers and biochemistry. Australasian Society for Ultrasound in Medicine 40th Annual Congress. Gold Coast, Brisbane, Australia. 24-26 September 2010. 105.Screening by midwives. Australasian Society for Ultrasound in Medicine 40th Annual Congress. Gold Coast, Brisbane, Australia. 24-26 September 2010. 106.Sonographic assessment of the fetus: moving to the first trimester. 中国超声医学工程学会 第三届全国妇产及计划生育超声医学学术会议,2010 年 9 月 11-12 日,中国成都。 107.Update on non-invasive screening for trisomy 21. 9th World Congress in Fetal Medicine. 2024 June 2010, Rhodes, Greece, 2010 108.Examination of the fetal heart with a matrix probe. 9th World Congress in Fetal Medicine. 20-24 June 2010, Rhodes, Greece, 2010 109.Twin pregnancies: Double happiness? XXII European Congress of Perinatal Medicine. 2629 May 2010, Granada, Spain. 110.Prenatal diagnosis: The way forward. Grand round as a full visiting professor of the Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, USA. 3-4 April 2010. 111.Cell-freee DNA / RNA. The 26th Fetus as a Patient International Congress. 25-28 Apr 2010, San Diego, USA. 112.Update on first trimester ultrasound. 17th Annual Congress of the Perinatal Society of Malaysia. 18-21 March 2010. Kula Lumpur, Malaysia. 113.Non-invasive prenatal diagnosis using cell free fetal DNA. 17th Annual Congress of the Perinatal Society of Malaysia. 18-21 March 2010. Kula Lumpur, Malaysia.

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114.Assessing risks in twin pregnancies. Ultrasound training program, in prenatal screening and diagnosis. 15-17 March 2010, Hanoi, Vietnam. 115.First Trimester Case Review. Ultrasound training program, in prenatal screening and diagnosis. 15-17 March 2010, Hanoi, Vietnam. 116.Examining the Brain at 20 weeks. Ultrasound training program, in prenatal screening and diagnosis. 15-17 March 2010, Hanoi, Vietnam. 117.Chorionicity – Clinical significance, pathophysiology, diagnosis. 复杂性双胎问题高峰论坛。 中国上海,2010 年 2 月 27 - 28 日。 118.Prenatal diagnosis and screening for chromosomal abnormalities。复杂性双胎问题高峰论 坛。中国上海,2010 年 2 月 27 - 28 日。 119.Overview of TTTS: Pathophysiology, incidence, prediction, diagnosis, treatment alternatives. 复 杂性双胎问题高峰论坛。中国上海,2010 年 2 月 27 - 28 日。 120.TRAP sequence: diagnosis and management. 复杂性双胎问题高峰论坛。中国上海,2010 年 2 月 27 - 28 日。 121.Delayed delivery of the second twin. 复杂性双胎问题高峰论坛。中国上海,2010 年 2 月 27 - 28 日。 122.Introduction to 1st trimester screening. 3rd Japan Ian Donald Ultrasound Advanced Seminar 2010. 13-14 February 2010, Osaka, Japan. 123.How to get NT certificate. 3rd Japan Ian Donald Ultrasound Advanced Seminar 2010. 13-14 February 2010, Osaka, Japan. 124.Non-invasive prenatal diagnosis. 3rd Japan Ian Donald Ultrasound Advanced Seminar 2010. 13-14 February 2010, Osaka, Japan. 125.Nuchal translucency and first trimester scan. ISUOG approved training course Beijing, China. 23-24 January 2010, Beijing, China. 126.Update on prenatal screening for Down syndrome. Obstetric Ultrasonographic Conference Macao 2010. 20-21 January 2010, Macau, China. 127.NT, pathophysiology and chromosomal defects. Obstetric Ultrasonographic Conference Macao 2010. 20-21 January 2010, Macau, China. 128.FMF guidelines on the measurement of NT. Obstetric Ultrasonographic Conference Macao 2010. 20-21 January 2010, Macau, China. 129.Chorionic villus sampling vs amniocentesis. Obstetric Ultrasonographic Conference Macao 2010. 20-21 January 2010, Macau, China.

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130.Complications of monochorionic twin pregnancies. Qatar Health 2009. 13-14 December 2009, Doha, Qatar. 131.Prenatal diagnosis – The way forward. Qatar Health 2009. 13-14 December 2009, Doha, Qatar. 132.产前诊断 : 发展与展望。全国产前诊断暨产前超声新技术新进展。中国广州,2009 年 11 月 27-29 日。 133.Pre-eclampsia in Hong Kong. 3rd SGI International Summit 2009: Preeclampsia. 12-14 November 2009, Sendai, Japan. 134.Should mid-trimester amniocentesis and PCR be an acceptable alternative to screening? 5th Asia Pacific Congress in Maternal Fetal Medicine. 6-8 November 2009, Hong Kong. 135.Management of single intra-uterine death in MC twin pregnancies. Congress in Maternal Fetal Medicine. 6-8 November 2009, Hong Kong. 5th Asia Pacific

136.Clinical use of maternal serum PlFG and sFlt-1 in Chinese women. 5th Asia Pacific Congress in Maternal Fetal Medicine. 6-8 November 2009, Hong Kong. 137.Prevention of preterm labour – Arabin pessary. 5th Asia Pacific Congress in Maternal Fetal Medicine. 6-8 November 2009, Hong Kong. 138.Private banking of umbilical cord blood stem cell for future autologous use. 5th Asia Pacific Congress in Maternal Fetal Medicine. 6-8 November 2009, Hong Kong. 139.产前诊断新进展。胎儿医学新进展学习班。中山大学附属第一医院,广东省优生优育 协会。中国广州,2009 年 9 月 25-27 日。 140.Invasive and non invasive diagnosis of chromosomal abnormalities. Pre-congress course: The new role of the 11-14 week scan. 19th World Congress on Ultrasound in Obstetrics and Gynecology. 13-17 September 2009, Hamburg, Germany. 141.Diagnosis of trisomy 21 by parallel genomic sequencing. 8th World Congress in Fetal Medicine. 28t June-2 July 2009, Portorose, Slovenia. 142.Targeted array CGH-based fetal DNA chip. 8th World Congress in Fetal Medicine. 28t June2 July 2009, Portorose, Slovenia. 143.Matrix probe in acquisition of a true midsagittal section. 8th World Congress in Fetal Medicine. 28t June-2 July 2009, Portorose, Slovenia. 144.关于这个培訓班及中华胎儿医学基金会产科超声资格认证。产科超声医师资格认证理 论课程培训班, 2009 年 5 月 21-24 日, 中国深圳。

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145.产科基本扫查技术及超声如何作为一项诊断和筛查工具。产科超声医师资格认证理论 课程培训班, 2009 年 5 月 21-24 日, 中国深圳。 146.超声预测胎儿孕龄及评估胎儿生长发育,宫内发育迟缓。产科超声医师资格认证理论 课程培训班, 2009 年 5 月 21-24 日, 中国深圳。 147.早孕超声筛查。产科超声医师资格认证理论课程培训班, 2009 年 5 月 21-24 日, 中国深 圳。 148.软标记。产科超声医师资格认证理论课程培训班, 2009 年 5 月 21-24 日, 中国深圳。 149.双胎输血的超声诊断和治疗。产科超声医师资格认证理论课程培训班, 2009 年 5 月 2124 日, 中国深圳。 150.对异常胎儿的进一步研究、病人的咨询及胎儿宫内治疗。产科超声医师资格认证理论 课程培训班, 2009 年 5 月 21-24 日, 中国深圳。 151.产前超声的常规, 标准和建议。产科超声医师资格认证理论课程培训班, 2009 年 5 月 21-24 日, 中国深圳。 152.Array CGH in prenatal diagnosis: Perspective from pregnant women. Agilent Asia Pacific Cytogenetics User Summit 2009. Singapore, 6-7 May 2009. 153.Epidemiology of twin multiples in Chinese population. 1st World Congress in Twin Pregnancy. 16-18 April 2009, Venice, Italy. 154.Prenatal diagnosis: What is ahead? The 9th Vietnam-France-Asia-Pacific Conference on reproductive health. 2-3 April 2009, Ho Chi Minh, Vietnam. 155.Racial variation in ultrasound and biochemical parameters used in first trimester screening. Pre-congress NT course. The Fetus as a Patient, XXV International Congress 2009. 6-8 March 2009, Sydney, Australia. 156.Down syndrome screening in Chinese populations at 11-14 weeks. The Fetus as a Patient, XXV International Congress 2009. 6-8 March 2009, Sydney, Australia. 157.Non-invasive prenatal diagnosis of chromosomal abnormalities and genetic syndromes. The Fetus as a Patient, XXV International Congress 2009. 6-8 March 2009, Sydney, Australia. 158.Prenatal diagnosis: What is ahead? HKCOG 20th Anniversary Symposium. 8-9 November 2008, Hong Kong. 159.Live 3D ultrasound and related technology. 4th Asia Pacific Congress in Maternal Fetal Medicine. 17-19 October 2008, Macau SAR, China. 160.Complication of monochorionic twin pregnancies. Cross-strait Tri-regional Ultrasound In Medicine Summit Forum. 11-12th October 2008, Xiamen, China.
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161.First trimester screening of fetal Down syndrome – experience in a Chinese population. The Fetus as a Patient, XXIV International Congress. 12-14th June 2008, Frankfurt, Germany. 162.New ultrasound markers of chromosomal abnormalities. The Fetus as a Patient, XXIV International Congress. 12-14th June 2008, Frankfurt, Germany. 163.Procedure-related fetal losses after invasive prenatal diagnostic procedures. The Fetus as a Patient, XXIV International Congress. 12-14th June 2008, Frankfurt, Germany. 164.Fetal products in maternal blood. 7th World Congress in Fetal Medicine. 22-26 June 2008, Sorrento, Italy. 165.True mid-sagittal section of the fetal face. 7th World Congress in Fetal Medicine. 22-26 June 2008, Sorrento, Italy. 166.胎儿超声标准切面与规范。第十一次广东省暨首届省港澳超声医学学术交流大会。中 国广州,2007 年 12 月 1-2 日。 167.Live 3D USG. Symposium on Perinatal Medicine 2007. 24-25th November 2007, Hong Kong. 168.The role of ultrasound in the screening and diagnosis of chromosomal abnormalities. The 8th Congress of the Asian Federation of Societies for Ultrasound in Medicine and Biology. 12-16 November 2007, Bangkok, Thailand. 169.Specific complications of monochorionic twins. The 8th Congress of the Asian Federation of Societies for Ultrasound in Medicine and Biology. 12-16 November 2007, Bangkok, Thailand. 170.量度 NT 的标准技巧。英国胎儿医学基金会超声筛查认证培训班。中国上海,2007 年 11 月 7 日。 171.The application of array comparative genome hybridization (aCGH). 8th World Congress of Perinatal Medicine. 9-13 September 2007, Florence, Italy. 172.Obstetric ultrasound: Training and quality assurance. 3rd Asia Pacific Congress in Maternal Fetal Medicine. 29-31 August 2007, Nanjing, China. 173.New markers for fetal Down syndrome screening. 3rd Asia Pacific Congress in Maternal Fetal Medicine. 29-31 August 2007, Nanjing, China. 174.Clinical research: Overcoming the obstacles. 3rd Asia Pacific Congress in Maternal Fetal Medicine. 29-31 August 2007, Nanjing, China. 175.Methods of targeting fetal products. 6th World Congress in Fetal Medicine. 17-21 June 2007. Cavtat, Croatia.

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176.Non-invasive prenatal diagnosis of fetal chromosomal abnormalities. International forum of preterm labor and fetal medicine in China. 19-20 May 2007. Chongqing, China. 177.Invasive tests in prenatal diagnosis. 7th International conference Vietnam-France-Asia Pacific. 17-18 May 2007. Ho Chi Ming City, Vietnam. 178.Ultrasound in first trimester. 7th International conference Vietnam-France-Asia Pacific. 1718 May 2007. Ho Chi Ming City, Vietnam. 179.Non-invasive prenatal diagnosis of chromosomal abnormalities. Postgraduate Seminar, Hong Kong College of Obstetricians and Gynaecologists. 29th April 2007. Hong Kong. 180.Down syndrome screening programme – Clinical Governance. Third ISUOG Obstetric Ultrasound Outreach Course. 13-15 April 2007. Singapore. 181.Assessment of fetal well being (including Doppler ultrasound). Third ISUOG Obstetric Ultrasound Outreach Course. 13-15 April 2007. Singapore. 182.Diagnostic and therapeutic fetoscopy. XXIII International Congress of the Fetus As A Patient International Society. 15-17 March 2007. Manila, Philippines. 183.Invasive in-utero therapy. XXIII International Congress of the Fetus As A Patient International Society. 15-17 March 2007. Manila, Philippines. 184.胎儿畸形产前超声诊断规范。第九届全国超声影像诊断及新进展学习班。中华医学超 声杂志(电子版)编辑部。中国昆明,2006 年 11 月 20-25 日 185.Current Status of Prenatal Screening for Fetal Down Syndrome. Institute of Biomedical Science Hong Kong Branch. 27th October 2006. 186.Advances in in-utero fetal therapy. 6th Perinatal Symposium 2006. The Obstetrical and Gynaecological Society of Hong Kong & The Hong Kong Society of Neonatal Medicine. 14th October 2006. Hong Kong. 187.Amniocentesis and chorionic villus sampling: experience from Hong Kong. 2nd Asia Pacific Congress in Maternal Fetal Medicine. 21-23 September 2006, Guangzhou, China. 188.Mode of delivery after previous Caesarean section. 2nd Asia Pacific Congress in Maternal Fetal Medicine. 21-23 September 2006, Guangzhou, China 189.Tocolytics: which and when?. 2nd Asia Pacific Congress in Maternal Fetal Medicine. 21-23 September 2006, Guangzhou, China 190.Gender-independent fetal DNA marker in pre-eclampsia. Fifth World Congress in Fetal Medicine. Barcelona, Spain. 25-29 June 2006.

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191.Ultrasound markers in the first trimester. Second ISUOG obstetric ultrasound outreach course (Singapore). Department of Maternal Fetal Medicine, KK Women’s & Children’s Hospital, Singapore. Singapore. 12th-14th May 2006. 192.应用颈皮厚度测量進行风险评估。英国胎儿医学基金会超声筛查认证培训班。深圳市 婦幼保健院,香港中文大学妇产科学系。中国深圳,2006 年 3 月 25-26 日。 193.应用孕早期胎儿鼻骨、三尖瓣血流、静脉导管血流和三维超声的风险评估。英国胎儿 医学基金会超声筛查认证培训班。深圳市婦幼保健院,香港中文大学妇产科学系。中 国深圳,2006 年 3 月 25-26 日。 194.序贯筛查及应变筛查。英国胎儿医学基金会超声筛查认证培训班。深圳市婦幼保健 院,香港中文大学妇产科学系。中国深圳,2006 年 3 月 25-26 日。 195.早期胎儿畸形的超声诊断。英国胎儿医学基金会超声筛查认证培训班。深圳市婦幼保 健院,香港中文大学妇产科学系。中国深圳,2006 年 3 月 25-26 日。 196.IUGR 二维超声评价。胎儿产前超声诊断与分析思维方法。深圳市婦幼保健院。中国 深圳,2006 年 3 月 27-31 日。 197.IUGR 的 Doppler 超声评价。胎儿产前超声诊断与分析思维方法。深圳市婦幼保健院。 中国深圳,2006 年 3 月 27-31 日。 198.中孕期超声应观察的内容。胎儿产前超声诊断与分析思维方法。深圳市婦幼保健院。 中国深圳,2006 年 3 月 27-31 日。 199.中孕期正常胎儿超声标准切面。胎儿产前超声诊断与分析思维方法。深圳市婦幼保健 院。中国深圳,2006 年 3 月 27-31 日。 200.中孕期常规超声扫描。胎儿产前超声诊断与分析思维方法。深圳市婦幼保健院。中国 深圳,2006 年 3 月 27-31 日。 201.Amniocentesis and CVS. Indonesian Society of Obstetricians and Gynaecologists, and the Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Bali, Indonesia. 23rd March 2006. 202.Risk assessment by maternal age and NT thickness. Indonesian Society of Obstetricians and Gynaecologists, and the Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Bali, Indonesia. 23rd March 2006. 203.Risk assessment by nasal bone, tricuspid flow, ductus venosus flow, and 3D ultrasound in the first trimester. Indonesian Society of Obstetricians and Gynaecologists, and the Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Bali, Indonesia. 23rd March 2006.

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204.Second trimester ultrasound markers. Indonesian Society of Obstetricians and Gynaecologists, and the Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. Bali, Indonesia. 23rd March 2006. 205.Complications of Monochorionic Twin Pregnancies. 1st Asia-Pacific Advanced Ultrasound Course in Obstetrics and Gynecology. Bali, Indonesia. 24th-25th March 2006. 206.入侵性产前诊断方法。河北省产前筛查与产前诊断培训班。河北省卫生厅妇幼处,河 北省人民医院。中国河北省石家庄市,2006 年 3 日 1-5 日。 207.篩查原理。河北省产前筛查与产前诊断培训班。河北省卫生厅妇幼处,河北省人民医 院。中国河北省石家庄市,2006 年 3 日 1-5 日。 208.染色体异常的中孕筛查。河北省产前筛查与产前诊断培训班。河北省卫生厅妇幼处, 河北省人民医院。中国河北省石家庄市,2006 年 3 日 1-5 日。 209.染色体异常的早孕筛查。河北省产前筛查与产前诊断培训班。河北省卫生厅妇幼处, 河北省人民医院。中国河北省石家庄市,2006 年 3 日 1-5 日。 210.序贯篩查。河北省产前筛查与产前诊断培训班。河北省卫生厅妇幼处,河北省人民医 院。中国河北省石家庄市,2006 年 3 日 1-5 日。 211.中孕期常规超声扫描。河北省卫生厅妇幼处,河北省人民医院。中国河北省石家庄 市,2006 年 3 日 1-5 日。 212.中孕期超声软标志物的处理。河北省卫生厅妇幼处,河北省人民医院。中国河北省石 家庄市,2006 年 3 日 1-5 日。 213.单绒毛膜双胎妊娠病理的诊断及预测。河北省卫生厅妇幼处,河北省人民医院。中国 河北省石家庄市,2006 年 3 日 1-5 日。 214.Recent advances in prenatal diagnosis and therapy. 2006 Dr. Stanley Ho Medical Development Foundation Symposium. Macau SAR, China. 7th January 2006. 215.中孕期超声标志物的处理。第七期全国产前诊断技术培训班。中国协和医科大学,北 京协和医院妇产科,哈尔滨医科大学附属第二医院。中国哈尔滨,2005 年 12 月 19-23 日。 216.中孕期超声筛查。第七期全国产前诊断技术培训班。中国协和医科大学,北京协和医 院妇产科,哈尔滨医科大学附属第二医院。中国哈尔滨,2005 年 12 月 19-23 日。 217.胎儿的宫内治疗。出生缺陷产前筛查与诊断学习班。卫生部医药卫生科技发展研究中 心,上海复旦大学附属妇产科医院。中国上海,2005 年 12 月 7-12 日。

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218.胎儿镜引导激光治疗双胎输血综合征。出生缺陷产前筛查与诊断学习班。卫生部医药 卫生科技发展研究中心,上海复旦大学附属妇产科医院。中国上海,2005 年 12 月 712 日。 219.11-14 周胎儿检查。出生缺陷产前筛查与诊断学习班。卫生部医药卫生科技发展研究 中心,上海复旦大学附属妇产科医院。中国上海,2005 年 12 月 7-12 日。 220.Using your machine: Volume measurement. 3D/4D Course in Obstetrics & Gynaecology. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong, and the International Academy of Medical Ultrasound (Asia). Hong Kong SAR. 26-27th November 2005. 221.Screening of fetal chromosomal abnormalities. 1st Asia Pacific Congress in Maternal Fetal Medicine. Hong Kong SAR. 14-16 October 2005. 222.应用颈皮厚度测量進行风险评估。英国胎儿医学基金会超声筛查认证培训班暨产前诊 断新技术、进展学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科 学系。中国广州,2005 年 7 月 16-21 日。 223.序贯筛查。英国胎儿医学基金会超声筛查认证培训班暨产前诊断新技术、进展学习 班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科学系。中国广州, 2005 年 7 月 16-21 日。 224.多胎妊娠染色体异常的筛查和诊断。英国胎儿医学基金会超声筛查认证培训班暨产前 诊断新技术、进展学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产 科学系。中国广州,2005 年 7 月 16-21 日。 225.筛查试验的实施。英国胎儿医学基金会超声筛查认证培训班暨产前诊断新技术、进展 学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科学系。中国广 州,2005 年 7 月 16-21 日。 226.唐氏综合征的孕中期生化筛查。英国胎儿医学基金会超声筛查认证培训班暨产前诊断 新技术、进展学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科学 系。中国广州,2005 年 7 月 16-21 日。 227.診断性及介入性胎儿镜。英国胎儿医学基金会超声筛查认证培训班暨产前诊断新技 术、进展学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科学系。 中国广州,2005 年 7 月 16-21 日。 228.侵入性胎儿治疗。英国胎儿医学基金会超声筛查认证培训班暨产前诊断新技术、进展 学习班。中国协和医科大学,广州市妇婴医院,香港中文大学妇产科学系。中国广 州,2005 年 7 月 16-21 日。

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229.母血循环中的胎儿核酸在产前诊断的意义。英国胎儿医学基金会超声筛查认证培训班 暨产前诊断新技术、进展学习班。中国协和医科大学,广州市妇婴医院,香港中文大 学妇产科学系。中国广州,2005 年 7 月 16-21 日。 230.Current Status of Down Syndrome Screening. CME program for non-fellows 2005, Hong Kong Academy of Medicine, Hong Kong. 11th May 2005. 231.Early onset IUGR – management dilemma. Postgraduate study day, Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong SAR. 10th May 2005 232.First trimester markers. First ISUOG Obstetric Ultrasound Outreach Course (Singapore). Department of Maternal Fetal Medicine, KK Women’s & Children’s Hospital. Singapore. 29th April- 1sst May 2005. 233.子宮內的胎儿治療及双胎输血綜合征胎儿镜下激光治疗。第五期全国产前诊断技术培 训班。中国协和医科大学,北京协和医院妇产科。中国北京,2005 年 4 月 17-23 日。 234.染色体异常的早孕筛查与诊断。第五期全国产前诊断技术培训班。中国协和医科大 学,北京协和医院妇产科。中国北京,2005 年 4 月 17-23 日。 235.单絨毛膜双胎妊娠病理的诊断及预测。上海復旦大学妇产科医院。中国上海,2005 年 4 月 16 日。 236.Detection of fetal pulmonary anomalies at 18-23 week. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 237.Abnormalities of multiple pregnancies. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 238.Detection of fetal anomalies of the face and neck at 18-23 week. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 239.Detection of fetal gastrointestinal anomalies at 18-23 week. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 240.Fetal Doppler. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 241.How to avoid medical litigation. Certificate course on 18-23 week scan, cervical assessment, placental & fetal Doppler. Hong Kong. 9th-10th April 2005. 242.子宮內的胎儿治療。围产医学技术及高危儿监测干预技术新进展研讨班。广东省妇幼 保健院。中国广州,2005 年 1 月 11-13 日。 243.双胎输血綜合征胎儿镜下激光治疗。围产医学技术及高危儿监测干预技术新进展研讨 班。广东省妇幼保健院。中国广州,2005 年 1 月 11-13 日。

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244.Amniocentesis and chorionic villus sampling. Certificate Course on 11-14 week scan. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong & Fetal Medicine Foundation, UK, 7th November 2004. 245.Increased nuchal translucency and normal karyotypes. Certificate Course on 11-14 week scan. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong & Fetal Medicine Foundation, UK, 7th November 2004. 246.Chorionicity and its consequences.. Certificate Course on 11-14 week scan. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong & Fetal Medicine Foundation, UK, 7th November 2004. 247.An one stop first trimester combined screening clinic for Donw’s syndrome in Hong Kong – a local experience. Perinatal Symposium 2004. The Obstetrical and Gynaecological Society of Hong Kong, the Hong Kong Society of Neonatal Medicine. Hong Kong. 30th October 2004. 248.双胎输血綜合征胎儿镜下激光治疗。全国产前诊断技术培训班。卫生部妇幼保健社区 卫生司及北京协和医院妇产科主办。中国成都,2004 年 10 月 13-16 日。 249.孕期胎儿核酸。全国产前诊断技术培训班。卫生部妇幼保健社区卫生司及北京协和医 院妇产科主办。中国成都,2004 年 10 月 13-16 日。 250.染色体异常的早孕筛查与诊断。全国产前诊断技术培训班。卫生部妇幼保健社区卫生 司及北京协和医院妇产科主办。中国成都,2004 年 10 月 13-16 日。 251.介入性宮內治疗。全国产前诊断技术培训班。卫生部妇幼保健社区卫生司及北京协和 医院妇产科主办。中国成都,2004 年 10 月 13-16 日。 252.双室双流出道。全国产前诊断技术培训班。卫生部妇幼保健社区卫生司及北京协和医 院妇产科主办。中国成都,2004 年 10 月 13-16 日。 253.Fetal nucleic acid in maternal blood. 产前诊断新技术进展学习班。Guangzhou MaternalNeonatal Hospital, Guangzhou, China. 24th August 2004. 254.双胎输血综合征的诊断与治疗新进展。产前诊断新技术进展学习班。Guangzhou Maternal-Neonatal Hospital, Guangzhou, China. 24th August 2004. 255.染色体异常的早孕筛查与诊断。产前诊断新技术进展学习班。Guangzhou MaternalNeonatal Hospital, Guangzhou, China. 24th August 2004. 256.Invasive fetal therapy. 临床胎儿医学新进展,国家级医学继续教育项目。Fetal Medicine Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. 5th August 2004.

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257.Second trimester routine scan. 临床胎儿医学新进展,国家级医学继续教育项目。Fetal Medicine Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. 5th August 2004. 258.Twin pregnancy. 临床胎儿医学新进展,国家级医学继续教育项目。Fetal Medicine Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. 5th August 2004. 259.Fetal urinary tract abnormalities. Post-graduate seminar. Guangzhou Maternal-Neonatal Hospital, Guangzhou, China. 24th July 2004. 260.Implementation of a combined test in a University Department. Nuchal translucency course, post-congress workshop. First International Scientific Meeting of the International Society of Ultrasound in Obstetrics and Gynecology. Singapore, 21st to 24th March 2004. 261.The 20 week marker scan revisited. Nuchal translucency course, post-congress workshop. First International Scientific Meeting of the International Society of Ultrasound in Obstetrics and Gynecology. Singapore, 21st to 24th March 2004. 262.First trimester combined screening for Down syndrome. CNE meeting, Union Hospital, Hong Kong, 22th November 2003 263.Amniocentesis and chorionic villus sampling. Certificate Course on 11-14 week scan. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong & Fetal Medicine Foundation, UK, 27th September 2003. 264.Chorionicity and its consequences. Certificate Course on 11-14 week scan. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong & Fetal Medicine Foundation, UK, 27th September 2003. 265.Midwives-led routine second trimester ultrasound – local experience. Symposium on Perinatal Medicine 2002. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong 7th-8th September 2002, Hong Kong. 266.Structural assessment – 4 chamber view. Symposium on Perinatal Medicine 2002. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong 7th-8th September 2002, Hong Kong. 267.Prepregnancy care – who, where, how? Postgraduate Study Day, Department of Obstetrics and Gynaecology, The University of Hong Kong. 15th January 2002. 268.Mothers with abnormal fetuses. Senior Trainee CAC, Hong Kong College of Psychiatrists. 9th November 2001, Hong Kong. 269.The role of invasive prenatal therapy – A local experience. Symposium on Perinatal Medicine 2001. Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong. 20th-21st October 2001, Hong Kong.

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270.Prophylaxis against eclampsia – The role of magnesium sulphate. CME lectures, Hong Kong Sanatorium & Hospital, Hong Kong. 10th October 2001. 271.Advances in antenatal diagnosis and management. Update series in child health 2001. Organised by the Hong Kong Paediatric Society, Hong Kong College of Paediatricians and Department of Health. Hong Kong. 22nd September 2001 272.Prental ultrasonographic diagnosis of nuchal cord. CME lectures, Baptist Hospital, Hong Kong. 13th September 2001 273.Recent advances in antenatal diagnosis. CME lectures, Union Hospital, Shatin, Hong Kong. 31st August 2001. 274.Clinical management of problematic pregnancy. Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, the Chinese University of Hong Kong. 25th August 2001 275.Misuses of ultrasound. Seminar on obstetric ultrasound for practising midwives. The Hong Kong Midwives Association. 18th August 2001 276.Ultrasound markers of chromosomal abnormalities. Seminar on obstetric ultrasound for practising midwives. The Hong Kong Midwives Association. 18th August 2001 277.Placental, liquor and Doppler. Seminar on obstetric ultrasound for practising midwives. The Hong Kong Midwives Association. 11th August 2001 278.Rising caesarean section rate – what should be done? HKCOG Postgraduate Seminar, Hong Kong Academy of Medicine Jockey Club Building. 13th May 2001. 279.Intrapartum monitoring of fetal oxygenation. Postgraduate Study Day, Department of Obstetrics and Gynaecology, University of Hong Kong. 11th December 2000. 280.Antenatal screening and prenatal diagnosis. Lecture for pupil midwives. School of midwifery, Prince of Wales Hospital. 5th December 2000. 281.Antenatal diagnosis of urinary tract abnormalities: an obstetric perspective. International symposium on antenatal diagnosis and fetal uropathy. Department of surgery, CUHK. 3rd December 2000. 282.Fetal Anatomy. Ultrasound Training Lectures 2000. O&G Ultrasound Training in HA Hospital, the Hospital Authority. 16th November 2000 283.Fetal anatomy. USG Lecture for trainee in HA hospitals. Hospital Authority. 18th November 2000 284.Prenatal Biochemical screening for Chromosome Abnormalities. Department of Chemical Pathology, CUHK. 26th November 1999

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285.Fetal Anatomy. Ultrasound Training Lectures 1999. O&G Ultrasound Training in HA Hospital, the Hospital Authority. 16th October 1999 286.Selective fetocide. Working Group on Prenatal Diagnosis and Counselling Services, the Hospital Authority. 9th October 1999 287.Pros and cons of electronic fetal heart rate monitoring – Special Diploma Course in Midwifery Practice, Department of Obstetrics and Gyaecology, The Chinese University of Hong Kong and School of Midwifery, Prince of Wales Hospital. 6 February 1999. 288.How useful is routine scans? Certificate in Obstetric and Midwifery Ultrasound for Practising Midwives. Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 19 September 1998. 289.In-utero management of fetal abnormalities. Hong Kong Academy of Medicine First International Congress, 26-29 November 1998 290.Chairman, Session of Obstetrics and Gynaecology, Hong Kong Academy of Medicine First International Congress, 26-29 November 1998. 291.Fetal measurements and estimation of gestational age in 2nd trimester. Certificate in Obstetric and Midwifery Ultrasound for Practising Midwives. Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 19 September 1998. 292.Understanding the ultrasound machine. Certificate in Obstetric and Midwifery Ultrasound for Practising Midwives. Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 19 September 1998. 293.Gynaecological surgeries. Diploma in Critical Care Nursing (97-98). Department of Nursing and Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong. 5th December 1997. 294.Management of breech presentation at term - Postgraduate Seminar, Current Practice in Obstetrics and Gynaecology. The Hong Kong College of Obstetricians & Gynaecologists. 16 November 1997. 295.Meconium stained liquor - implications on obstetric management. Postgraduate study day, Department of Obstetrics and Gynaecology, The University of Hong Kong. Hong Kong. 12th August 1997. 296.Prenatal diagnosis - future development and research. The first Guangdong, Hong Kong & Macau Sympsium on maternal and Child Health Care. GuangZhou, China. 23-25 June 1997. 297.Prenatal diagnosis update. Enhancement course in Obstetrics and midwifery. School of midwifery, Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 7 May 1997.

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298.Gynaecological surgeries. Diploma in Critical Care Nursing (96-97). Department of Nursing and Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong. March 1997. 299.Biochemical screening for Down’s Syndrome. Lectures on prenatal diagnosis and counselling organized by the Working Group on Prenatal Diagnostic & Counselling Service of the Hospital Authority, 6 July 1996. 300.Down’s screening - serum and ultrasound. Certificate in Obstetric and Midwifery Ultrasound for Practising Midwives. Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 22 June 1996. 301.Fetal measurements and estimation of gestational age in 2nd trimester. Certificate in Obstetric and Midwifery Ultrasound for Practising Midwives. Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 19 Apr 1996. 302.Gynaecological surgeries. Diploma in Critical Care Nursing (95-96). Department of Nursing and Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong. 22 December 1995. 303.Hysteroscopic surgical procedures. Workshop on Gynaecological Endoscopic Surgery for Theatre Nurses. 23 July 1995. 304.Instrumentation for laparoscopic surgery. Workshop on Gynaecological Endoscopic Surgery for Theatre Nurses. 23 July 1995. 305.Hysteroscopic resection of submucosal fibroids. In Advanced Operative Endoscopy in Gynaecology. Organized by the Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong. 15-17 January 199

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