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Optimization of Douchi Fibrinolytic Enzyme Production by Statistical Experimental Methods


J   Hu a z h o n g   U n i v   S c i   T e c h n o l[ Me d   S c i ]   DO I   l O . 1 0 0 7 / s l 1 5 9 6 . O 1 3 — 1 0 8 9 — 8   1 5 3   Op t i mi z a t i o n   o f   Do u c h   Fi b r i n o l y t i c   En z y me   Pr o d u c t i o n   b y   S t a t i s t i c a l   Ex pe r i me n t a l   M e t ho ds ’   Xu   Z HA NG( 张 旭)   , L u o - j i a   Y UN( 运珞珈)  , L i a n g . b i n   P E NG( 彭 良斌)   , Y i   L U( 鲁 翌)   , K u n . p e n g   MA( 马鲲鹏)   ,   F e i T A NG( 唐 非)   MO E   K e y   L a b   o fE n v i r o n m e n t   a n d   He a l t h , 2 De p a r t me n t   o f E p i d e mi o l o g y   a n d   He a l t h   S t a t i s t i c s , S c h o o l   o fP u b l i c   He a l t h , T o n g j i   Me d i c a l C o l l e g e , Hu a z h o n gU n i v e r s i t yo f S c i e n c e a n dT e c h n o l o g y , W u h a n   4 3 0 0 3 0 , C h i n a   ◎ Hu a z h o n g   Un i v e r s i t y   o f S c i e n c e   a n d   T e c h n o l o g y   nd a   S p r i n g e r - Ve r l a g   Be r l i n   He i d e l b e r g   2 01 3   S u m ma r y: T h r o mb u s   d i s e a s e , o n e   o f   t h e   c o mm o n   c a r d i o v a s c u l a r   d i s e a s e s , h a s   a t t r a c t e d   wo r l d wi d e   a t .   t e n t i o n   f o r   i t s   is r i n g   mo r t a l i y  t a n d   mo r b i d i y. t Du e   t o   t h e   d i s t i n c t   s h o ta r g e s   o f   c u r r e n t   i f b r i n o l y t i c   d r u g s ,   n e w  i f b in r o l  ̄i c   a g e n t s   wa r r nt a   i n v e s t i g a t i o n . I n   t

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