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high-temperature, high-pressure (PARR) reactor is proposed for optimizing the extraction of phenolic


Brassinosteroid: a biotechnological target for enhancing crop yield and stress

Review Article New Biotechnology, Volume 26, Issues 3-4, 31 October 2009, Pages 131-136 Uday K. Divi, Priti Krishna Purchase
tolerance
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$ 31.50

Abstract | Figures/Tables | References Brassinosteroids (BRs) are a group of naturally occurring plant steroidal compounds with wide ranging biological activity. Because BRs control several important agronomic traits such as flowering time, plant architecture, seed yield and stress tolerance, the genetic manipulation of BR biosynthesis, conversion or perception offers a unique possibility of significantly increasing crop yields through both changing plant metabolism and protecting plants from environmental stresses. Genetic manipulation of BR activity has indeed led to increases in crop yield by 20–60%, confirming the value of further research on BRs to improve productivity.

Article Outline

Introduction BR signaling BR biosynthesis genes Engineering BR levels and sensitivity to increase yield Engineering BR levels to increase stress tolerance Future directions Acknowledgements References Serenoa repens: The Scientific Basis for the Treatment of Benign

127

Review Article European Urology Supplements, Volume 8, Issue 13, December 2009, Pages 887-893 Purchase $ 31.50 Fouad K. Habib
Prostatic Hyperplasia
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Abstract

Context

Medical therapies derived from natural sources have been used for centuries. Many are as effective as synthetic medications. The use of plant-derived medications for benign prostatic hyperplasia (BPH) is no exception. In particular, extracts of Serenoa repens (SrE), the fruit of the American dwarf palm, are widely available, and their use is rising throughout the world.

Objective

The underlying basis for SrE popularity stems from its safety and tolerability profile. However, despite its extensive use, its mechanism of action has not been definitely clarified. In this paper, we analyse the scientific basis for SrE efficacy in the treatment of BPH and explore the mechanisms by which its effects are induced.

Evidence acquisition

This literature review focuses on the actions of the lipidosterolic SrE on a host of targets. Several cellular and molecular techniques have been used to characterise the biologic pathways that may mediate these actions. Morphologic studies have been carried out to identify the changes of prostate ultrastructure and to determine modifications that may shed light on the mechanisms underlying SrE efficacy.

Evidence synthesis

Selectivity of the action of SrE for the prostate has been demonstrated. There are several morphologic changes, and these are accompanied by an increase

in the apoptotic index of the gland, along with inhibition of the activity of the 5α-reductase isoenzymes. The drug also acts on a number of other biologic systems and shows a capacity to moderate the androgenic, apoptotic, and inflammatory pathways of the cell. These pathways have been implicated in the hyperplastic process.

Conclusions

The interaction between prostate cells and SrE is manifest at several levels of the gland's biological spectrum and results in antiandrogenic, anti-inflammatory, and proapoptotic effects. These effects may account for the beneficial response triggered in some patients with BPH treated with SrE.

Article Outline

1. Introduction 2. Evidence acquisition 3. Evidence synthesis 3.1. Organ specificity of Serenoa repens 3.2. Antiandrogenic activities of Serenoa repens 3.3. Anti-inflammatory properties of Serenoa repens 3.4. The proapoptotic characteristics of Serenoa repens 3.5. Are all brands of Serenoa repens equal? 4. Conclusions Conflicts of interest Funding support References

Take Home Message

Serenoa repens (saw palmetto) extracts are complex mixtures of compounds that act simultaneously on

several biologic pathways known to be associated with the development of benign prostatic hyperplasia (BPH) in man. Reversal of the prohyperplastic pathways by the drug accounts for its clinical efficacy in the treatment of BPH. The fate and toxicity of the flavonoids naringenin and formononetin in

128

Original Research Article Soil Biology and Biochemistry, Volume 40, Issue 2, February 2008, Pages 528-536 Purchase $ 31.50 Liz J. Shaw, John E. Hooker
soil
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Abstract

The flavonoid class of plant secondary metabolites play a multifunctional role in below-ground plant–microbe interactions with their best known function as signals in the nitrogen fixing legume–rhizobia symbiosis. Flavonoids enter rhizosphere soil as a result of root exudation and senescence but little is known about their subsequent fate or impacts on microbial activity. Therefore, the present study examined the sorptive behaviour, biodegradation and impact on dehydrogenase activity (as determined by iodonitrotetrazolium chloride reduction) of the flavonoids naringenin and formononetin in soil. Organic carbon normalised partition coefficients, log Koc, of 3.12 (formononetin) and 3.19 (naringenin) were estimated from sorption isotherms and, after comparison with literature log Koc values for compounds whose soil behaviour is better characterised, the test flavonoids were deemed to be moderately sorbed. Naringenin (spiked at 50 μg g ) was biodegraded without a detectable lag phase with concentrations reduced to 0.13± 0.01 μg g
?1 ?1

at the end of the

96 h time course. Biodegradation of formononetin proceeded after a lag phase of 24 h with concentrations reduced to 4.5± 1% of the sterile control after

72 h. Most probable number (MPN) analysis revealed that prior to the addition of flavonoids,
5 ?1

the

soil

contained

5.4×10 MPN g catabolic

6

?1

(naringenin)

and

7.9×10 MPN g

(formononetin)

microbes.

Formononetin

concentration had no significant (p>0.05) effect on soil dehydrogenase activity, whereas naringenin concentration had an overall but non-systematic impact (p=0.045). These results are discussed with reference to likely total and bioavailable concentrations of flavonoids experienced by microbes in the rhizosphere.

Article Outline

1. Introduction 2. Materials and methods 2.1. Soil and flavonoids 2.2. Construction of flavonoid sorption isotherms 2.3. Flavonoid biodegradation 2.4. Most probable number determinations 2.5. Dehydrogenase assay 2.6. High performance liquid chromatography (HPLC) 3. Results 3.1. Adsorption isotherms 3.2. Biodegradation and most probable number analysis 3.3. Naringenin and formononetin impacts on dehydrogenase activity 4. Discussion 4.1. Sorption 4.2. Biodegradation of naringenin and formononetin 4.3. Toxicity 5. Conclusion Acknowledgements Appendix:. Calculation of a total soil concentration for naringenin from an aqueous phase concentration, taking into account naringenin partitioning behaviour in soil

References

129

Catalytic removal of NO and PAHs over AC-supported catalysts from incineration flue gas: Bench-scale and pilot-plant tests

Original

Research Article Chemical Engineering Journal, In Press, Corrected Proof,Purchase $ 31.50 Available online 6 March 2011 Hui-Hsin Tseng, Chi-Yuan Lu, Feng-Yim Chang, Ming-Yen Wey, Han-Tsung Cheng
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Abstract

For dioxin removal from incineration flue gas, the common method is absorption using activated carbon (AC). In order to reduce the consumption of energy, it is worth to evaluate the destruction removal efficiency (DRE) of NO and polycyclic aromatic hydrocarbons (PAHs) over AC with a few metals loading while dioxin is physical absorbed by AC. As a result, in the present work, the use of AC as a catalyst support for simultaneous NO reduction and PAHs catalytic oxidation was investigated as an alternative technology to improve incinerator processes. This study examined the selective removal of NO and PAHs from incineration flue gas containing O 2, N2, CO2, H2O, NO, organic compounds and fly ash over M/AC catalysts (M = Fe, Co, Ni, and Cu) using bench-scale and pilot-plant tests. Investigations on the effects of the incineration flue gas composition and the structure of the metal active site on NO and PAHs conversion revealed that the conversion activity increases as the atomic number of the transition metals increase, except for Ni. Carbon monoxide can act as a reductant to increase the NO removal efficiency. The M/AC catalysts showed high reactivity for simultaneous PAHs oxidation and NO reduction. The results provide useful information for the design and application of AC injection or selective catalyst reduction systems for waste incineration plants.

Article Outline

1. Introduction 2. Experimental 2.1. Catalyst preparation 2.2. Catalyst characterization 2.3. Bench-scale testing 2.4. Pilot-plant testing 3. Results and discussion 3.1. Catalyst characterization 3.2. Bench-scale testing: effect of the chemical state of the active site 3.3. Bench-scale testing: effect of gas composition 3.4. Bench-scale testing: poisoning of M/AC catalysts 3.5. Pilot-plant testing 4. Conclusions References

130

Changes in apolar metabolites during in vitro organogenesis of

Original Research Article Plant Physiology and Biochemistry, Volume 48, Issues 10-11, October-November 2010, Pages 827-835 Purchase Strahil Berkov, Atanas Pavlov, Vasil Georgiev, Jost Weber, Thomas$ 31.50 Bley, Francesc Viladomat, Jaume Bastida, Carles Codina
Pancratium maritimum
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Abstract

Calli, shoot-clumps and regenerated plants were initiated from young fruits of Pancratium maritimum L. Their genetic stability was monitored by flow cytometry before chemical studies. Apolar metabolites (alkaloids extracted at pH > 7, free fatty acids and fatty alcohols, sterols etc.) were qualitatively and

quantitatively analyzed by GC–MS. The results clearly demonstrated that alkaloid synthesis in P. maritimum is closely related with tissue differentiation. The highest amounts of alkaloids and presence of homolycorine and tazettine type compounds (end products of the biosynthetic pathway of the Amaryllidaceae alkaloids) were found in highly differentiated tissues. Galanthamine accumulated in the leaves of plantlets. The amount of hordenine, a protoalkaloid, is related with the ability of tissues to synthesize alkaloids. Saturated fatty acids were found in considerably higher levels in undifferentiated callus cultures and partially differentiated shoot-clumps than in regenerated plants. Mono- and dienoic fatty acids were found at higher levels in non-photosynthesizing tissues – calli, and in vitro and intact bulbs, while α-linolenic acid (trienoic acid) was found in higher amounts in the photosynthesizing leaves of shoot-clumps and regenerated plants than in bulbs and calli. Fatty alcohols were found mainly in leaves, while sterols tended to accumulate in photosynthesizing and undifferentiated tissues.

Article Outline

1. Introduction 2. Results and discussions 2.1. In vitro cultures 2.2. Apolar metabolites 2.2.1. Alkaloid profiles 2.2.2. Lipid profiles 3. Materials and methods 3.1. Plant material 3.2. In vitro cultures 3.2.1. Callus induction 3.2.2. Shoot formation

3.2.3. In vitro plant regeneration 3.3. Metabolite extraction 3.4. GC/MS analysis 3.4.1. Chromatographic conditions 3.4.2. Alkaloid quantification 3.5. Identification of the metabolites 3.5.1. Alkaloids 3.5.2. Lipids 3.5.3. Statistical analysis 3.6. Flow cytometry Acknowledgements References

Research Highlights

?Metabolites in Pancratium maritimum. Isolation and characterization of secondary metabolites from the

131

Original Research Article Asian Pacific Journal of Tropical Medicine, Volume 3, Issue 8, August 2010, Pages 602-604 Purchase $ 31.50 Elsa Lycias Joel, Valentin Bhimba
mangrove plant Rhizophora mucronata
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Abstract | References

Abstract
Objective

To evaluate the antibacterial activity of foliar extracts of Rhizophora mucronata (R. mucronata) against pathogens belonging to human origin and to identify the compound hitherto unprecedented in nature by GC-MS analysis.

Methods

Soxhlet extraction method was used to get the corresponding extracts of ethanol, petroleum ether, acetone, methanol and ethyl acetate. The antimicrobial activities of the organic solvent extracts on the various test organisms using agar well diffusion technique were carried out. Ethyl acetate extract exhibited promising antimicrobial activity and hence minimum inhibitory concentration (MIC) was performed for the same. Column chromatography was done for partial purification of crude extract and fractions were analyzed by GC-MS.

Results

A column chromatographic fractionation of the extracts and further UV visible and GS-MS analysis suggested the active principle compound were a mixture of squalene (19.19%), n-Hexadecanoic acid (6.59%), phytol (4.74%), 2-cyclohexane-1-one, 4-hydroxy-3,5, (4.20%) and oleic acid (2.88%).

Conclusions

The results are good enough to serve to transform the practice of research in this sub field across a range of different benefit streams that include drug development. By and large this type of structure analyses are most important as aids to more rational decision taking in safety models versus effectiveness. In general, structural data provide prima facie support for drug hypothesis.

132

Kinetic

model

development

and

simulation

of

simultaneous

hydrodenitrogenation and hydrodemetallization of crude oil in trickle bed

Original Research Article Fuel, Volume 90, Issue 6, June 2011, Pages 2165-2181 Aysar T. Jarullah, Iqbal M. Mujtaba, Alastair S. Wood
reactor
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Purchase
$ 37.95

Abstract | Figures/Tables | References

Abstract

One of the more difficult tasks in the petroleum refining industries that have not been considered largely in the literature is hydrotreating (HDT) of crude oil. The accurate calculations of kinetic models of the relevant reaction scheme are required for obtaining helpful models for HDT reactions, which can be confidently used for reactor design, operating and control. In this work, an optimization technique is employed to evaluate the best kinetic models of a trickle bed reactor (TBR) process utilized for hydrodenitrogenation (HDN) and hydrodemetallization (HDM) that includes hydrodevanadization (HDV) and hydrodenickelation (HDNi) of crude oil based on pilot plant experiments. The minimization of the sum of the squared errors (SSE) between the experimental and estimated concentrations of nitrogen (N), vanadium (V) and nickel (Ni) compounds in the products is used as an objective function in the optimization problem to determine the kinetic parameters.

A series of experimental work was conducted in a continuous flow isothermal trickle bed reactor, using crude oil as a feedstock and the commercial cobalt–molybdenum on alumina (Co–Mo/γ-Al2O3) as a catalyst.

A three-phase heterogeneous model based on two–film theory is developed to describe the behaviour of crude oil hydroprocessing in a pilot–plant trickle bed reactor (TBR) system. The hydroprocessing reactions have been modelled by power law kinetics with respect to nitrogen, vanadium and nickel compounds, and with respect to hydrogen. In this work, the gPROMS (general PROcess Modelling System) package has been used for modelling, simulation and parameter estimation via optimization. The model simulations results were found to agree well with the experiments carried out in a wide range of the studied operating conditions. The model is employed to predict the

concentration profiles of hydrogen, nitrogen, vanadium and nickel along the catalyst bed length in three phases.

Article Outline

Nomenclature 1. Introduction 2. Mathematical model of TBR for HDN, HDV and HDNi reactions 2.1. Mass balance equations 2.2. Chemical reaction rate 2.3. Reactor performance 2.4. Kinetic parameters of the models 3. Parameter estimation techniques 3.1. Optimization Problem Formulation for Parameter Estimation 4. Experimental work 4.1. Materials 4.2. Equipment and procedure 4.3. Experimental runs 5. Results and discussions 5.1. Experimental results 5.2. Estimation of kinetic parameters 5.3. Simulation of the HDN, HDNi and HDV Pilot Plant Reactor 6. Conclusions References

133

Photocatalytic degradation of emerging contaminants in municipal wastewater treatment plant effluents using immobilized TiO2 in a solar

Original Research Article Applied Catalysis B: Environmental, Volume 103, Issues 3-4, 5 AprilPurchase $ 41.95 2011, Pages 294-301 N. Miranda-Garcí S. Suárez, B. Sánchez, J.M. Coronado, S. a, Malato, M. Ignacio Maldonado
pilot plant
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Abstract

This article reports on degradation using TiO2 immobilized on glass spheres of 15 emerging contaminants (ECs) at low concentrations in simulated and real Municipal Wastewater Treatment Plant (MWTP) effluents. A sol containing titanium isopropoxide, commercial P25 and polyethylene glycol (PEG) was prepared, and a layer of the photoactive precursor was immobilized on glass spheres by dip-coating. The raw materials and the xerogels were characterized by N2 adsorption/desorption, XRD and TGA-DTA. The xerogel showed the TiO2 anatase, rutile and brookite crystal phases characteristic of the reference materials. The diffraction pattern showed no modification of the crystal size from incorporation of the PEG. Two different TiO2 anatase crystal sizes were identified, which was attributed to the different TiO2 precursors used in the synthesis route. Degradation of the emerging contaminants (acetaminophen, antipyrine, atrazine, carbamazepine, diclofenac, flumequine, hydroxybiphenyl, ibuprofen, isoproturon, ketorolac, ofloxacin, progesterone, sulfamethoxazole and triclosan), at an initial concentration of 100 μg L
?1

each was determined by

ultra-performance liquid chromatography (UPLC-UV) and mineralization was monitored by measuring the dissolved organic carbon (DOC). The experiments were performed in a pilot compound parabolic collector (CPC) solar plant at the Plataforma Solar of Almeria (Spain). 85% of the compounds were degraded within 120 min of illumination time depending on the water. The results show the potential application of this technology as a good alternative to suspension systems for the treatment of polluted water.

Article Outline

1. Introduction 2. Experimental

2.1. Reagents for analytical determinations 2.2. Contaminated water 2.3. Preparation of the catalyst 2.4. Characterization techniques 2.5. Experimental set-up 3. Analytical determinations 4. Results and discussion 4.1. Characterization results 4.2. Photocatalytic activity: results 4.3. TiO2 immobilized tests using SW and SE 4.4. Immobilized TiO2 tests in RE 5. Conclusions Acknowledgements References

Graphical abstract

Research highlights

? Development of a new sol to cover a borosilcate glass spheres. ? Coupling the new catalyst in a CPC reactor. ? Application of this system in treatment of emerging contaminants present in urban wastewater.

134

Establishment of transgenic tobacco hairy roots expressing basic peroxidases and its

application for phenol removal Original

Research Article Journal of Biotechnology, Volume 139, Issue 4, 23 February 2009,Purchase $ 37.95 Pages 273-279 Lucas G. Sosa Alderete, Melina A. Talano, Sabrina G. Ibá?ez, Silvia Purro, Elizabeth Agostini, Silvia R. Milrad, Marí I. Medina a
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Abstract

Transgenic hairy root (HR) systems constitute an interesting alternative to improve the efficiency of phytoremediation process. Since peroxidases (Px) have been associated with phenolic compounds removal, in the present work, transgenic tobacco HR, which expressed basic Px genes from tomato (tpx1 and tpx2), were established and assayed for phenol removal. Tobacco HR clones were obtained, including those transgenic for TPX1 or TPX2, those double transgenic (DT) for both Px and the corresponding controls. Based on growth index, the presence of rol C sequence, tpx1 and/or tpx2 genes and the coded proteins, as well as Px activity determinations, we selected 10 tobacco HR clones for phenol removal assays. The removal efficiencies were high for all the HR, although, some transgenic HR showed significantly higher removal efficiencies compared with controls. The results demonstrate that TPX1 is involved in phenol removal not only when it was overexpressed in tomato, but also when it was expressed in other plant, such as tobacco. The higher efficiency of TPX2 transgenic HR showed that this Px also participates in the process. The contribution of other mechanisms (adsorption, H 2O2 independent enzymatic processes) could be considered depreciable, which establishes the

great implication of Px in phenol removal.

Article Outline

1. Introduction 2. Material and methods 2.1. Plant material 2.2. Plant transformation with A. rhizogenes 2.3. PCR analysis 2.3.1. Amplification of rol C gene 2.3.2. Amplification of CaMV35S-tpx1 and CaMV35S-tpx2 constructions 2.4. Growth index (GI) analysis 2.5. Total and differential enzyme extraction and in vitro peroxidase activity 2.6. Analysis of isoperoxidase patterns 2.7. Removal assays and residual phenol determination 2.8. Statistical analysis 3. Results and discussion 3.1. Establishment of tobacco HR clones 3.2. Evaluation of GI 3.3. Molecular analysis of HR cultures 3.3.1. Amplification of rol C gene by PCR analysis 3.3.2. Amplification of CaMV35S-tpx1 and CaMV35S-tpx2 constructions by PCR analysis 3.4. Peroxidase activity determination and isoenzymes profiles 3.5. Removal phenol assays and determination of residual phenol 4. Perspectives Acknowledgements References

135

Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA)

Phytomedicine, Volume 17, Issue 2, February 2010, Pages 142-145 A. Tohidpour, M. Sattari, R. Omidbaigi, A. Yadegar, J. Nazemi
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$ 31.50

Abstract | Figures/Tables | References

Abstract

Antimicrobial properties of plants essential oils (EOs) have been investigated through several observations and clinical studies which purpose them as potential tools to overcome the microbial drug resistance problem. The aim of this research is to study the antibacterial effect of two traditional plants essential oils, Thymus vulgaris and Eucalyptus globulus against clinical isolates of Methicillin resistant Staphylococcus aureus (MRSA) and other standard bacterial strains through disk diffusion and agar dilution methods. Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) analysis examined the chemical composition of the oils. Results revealed both of oils to possess degrees of antibacterial activity against Gram (+) and Gram (–) bacteria. T. vulgaris EO showed better inhibitory effects than E. globulus essential oil. GC analysis of T. vulgaris resulted in thymol as the oil major compound whereas GC/MS assay exhibited eucalyptol as the most abundant constitute of E. globulus EO. These results support previous studies on these oils and suggest an additional option to treat MRSA infections. Clinical and further analytical trials of these data are necessary to confirm the obtained outcomes.

Article Outline

Introduction Material and methods Organisms and growth conditions Preparation of DNA PCR amplification

Essential oil extraction Quantification and Identification Antimicrobial assay Disk diffusion assay Agar dilution method Results Conclusion and discussion Acknowledgements References

现场应用科学家 Field Application Scientist (第二代基因测序 NGS)
Life Technologies
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粉丝团(3)|

公司行业: 公司性质: 公司规模:

制药/生物工程 外资(欧美) 500 人以上 比比你的竞争力

发布日期: 工作年限: 职位描述 工作经验:1-3 年 最低学历:博士

2011-04-15 一年以上

工作地点: 学 历:

北京 博士

招聘人数:

1

职位描述/要求: PURPOSE * Be a provider of technical and applications support to our installed and potential SOLiD and Ion Torrent customer base in China * Be a technical product champion through the provision of knowledge and practical skills relating to multiple Next-Generation sequencing applications * Assist with SOLiD and PGM instrument installations and applications by providing on-site customer training covering instrument operation and software applications together with reagent and consumable utilization * Training of other Life Technologies staff on the applications and technology basics of SOLiD and Ion Torrent sequencing

POSITION SCOPE * This role is equally focused on driving excellence in customer applications & technical support for post-sales installation, training and troubleshooting * Interacts with Life Technologies customers, field sales, sales managers, product marketing and technical support staff * Works closely with customers, APAC and US applications specialists to optimize application workflows of existing and new applications on SOLiD and Ion Torrent systems * Perform duties as described above and below across China and potentially APAC on an business needs basis KEY RESPONSIBILITIES Pre-sale Technical Expert * Assist the pre-sales process by demonstrating the technical advantages of Life Technologies products to customers and field staff via seminars, Webex training and coordination of demonstrations to be run both locally and in the US * Work with product marketing managers and sales staff to ensure Life Technologies provides excellent customer support for our Next Generation Sequencing platforms * Work with customers to fully understand Next Generation Sequencing technology and help define experimental protocols for SOLiD and Ion Torrent Technical Champion * Act as a technical resource for Sales and Marketing * Provide product marketing managers with applications advice, ensuring products are targeted well and the most appropriate product is sold in order to satisfy the customer needs and expectation * Assist customers to utilise instrument and reagent systems both efficiently and effectively so as to maximise customer satisfaction as well as revenues for Life Technologies

Support the current and new customer base by * Resolve technical queries quickly and expertly either over the phone or by visiting a customer site Facilitate training of the customer base by * Conduct customer training of instrument, software, and reagent consumable systems where applicable * Conduct workshops highlighting the technical advantages of Life Technologies sequencing technology solutions Attend customer sites when a systems failure is evident * Identify faulty reagents, processes or hardware where they adversely effect system performance Training of other Applied Biosystems staff * Conduct in-house training of Sales, Marketing and Support staff wherever a need is identified * Facilitate and co-ordinate product trials locally Applications Development * Identify market potential for new products and explore new opportunities by closely aligning with field sales and our customers Consumable Sales * Integrate with marketing, sales and support initiatives to drive reagents sales upon Next Generation Platforms

REQUIREMENTS SKILLS/EXPERIENCE * Ability to travel extensively within the territory to carry out primary responsibilities. * Excellent scientific skills in the areas of PCR, SDS, sequencing and fragment analysis * Leadership o Acts in accordance with the moral and ethics of the organisation o Strives for excellence and sets good examples for others o Steps forward to address difficult issues o Inspires confidence and respect * Communication o Excellent listening, questioning and negotiation skills o Ability to express ideas clearly and concisely orally and in writing o Comfortable in delivering presentations o Ability to share information clearly and consistently with colleagues * Self-motivated and engaged

o Goal-oriented o Able to work effectively across functional groups to meet aggressive schedules o Able to work with minimal supervision while maintaining focus and productivity o Consistently maintain a high level of energy and enthusiasm o A positive, motivating force in the workplace o Ability to adapt quickly to change o Excellent time management skills * Teamwork o Participative and collaborative management and operational work style * Customer focus o Ability to think and implement from a customer-centric perspective * Integrity and Judgement o Maintain and promote social, ethical and organisational norms in conducting all affairs o Ability to act responsibly and be trusted o To make well-reasoned and timely decisions, understanding of consequences. o Ability to think and act effectively, acting for the greater good of the organisation

EDUCATION * HIgher in a scientific discipline (HTP Genomics, molecular biology, genetics or biochemistry) preferred 联系方式: 应聘者请将中英文简历邮件发送至: cn.recruit@invitrogen.com

公司名称:美国 INVITROGEN 生命技术公司 公司地址:上海市虹桥路 1 号港汇中心一座 17 层 北京市朝阳区东三环北路 2 号南银大厦 17 层 传真: 公司主页:www.lifetechnologies.com 联系方式 电子邮箱: cn.recruit@invitrogen.com

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美国生命技术公司(翻译名称,Life Technologies)是一家致力于改善人类生存条件的全球性生 物技术工具公司,为全球 160 多个国家和地区的客户,包括学术研究机构、制药行业、生物科技行 业、法医鉴定实验室,食品安全实验室, 诊断公司等致力于利用生命科学改善人类生活的客户提 供超过 50,000 种基础生命科技产品、系统、服务与专业知识。 2010 年,公司销售额为 36 亿美元, 在全球拥有员工 11,000 多人。公司在研发方面的投入超过 3 亿美元并持有 3,900 多个专利和专有 许可。 生命技术公司是由 Invitrogen 公司和美国应用生物系统公司(Applied Biosystems)于 2008 年 11 月合并而成,公司合并后继续使用这两个知名品牌为客户提供服务。 前 Invitrogen 公司是为 多种应用平台提供试剂和耗材的一流供应商,前应用生物系统公司则是在基因测序,基因组和细胞 分析产品等领域为客户提供端到端解决方案的顶级供应商。 合并后的公司为更多的客户提供系统 的生命技术解决方案, 积极地促进应用于学术研究、新药开发、毒物学和法医学、疾病诊断、临 床细胞疗法和再生医学以及生物制剂的生产等领域技术的发展。美国有超过 90%的研究实验室在使 用我们的产品。 生命技术公司在亚太地区设有 15 个办事处和 8 个生产基地。拥有员工 1,200 人。此外,公司在亚 太区还建有 6 个客户服务中心和 7 个分销中心。 亚太地区是公司未来业务增长的亮点,根据生物产品的特点,公司在着力满足本地区客户的需求的 基础上,不断提高本地区的生产和研发以及物流配送能力。为了更多更快地培养国际化人才,公司 在澳大利亚、中国和新加坡设有三个培训基地,除了员工的培训,公司还力求为本地区的客户提供 培训的机会。 以“塑造发现,改善生活”为使命,生物技术产品与人们的健康和生活息息相关。与在世界其他国 家和地区一样, 我们正携手亚太各国的合作伙伴共同为应对人类的挑战和确保人类健康安全而积极 努力! Life Technologies 美国生命技术公司驻华各地机构 Life Technologies 上海亚太区总部 地址:上海市虹桥路 1 号港汇中心一座 17 层 Life Technologies 上海生产基地 地址:上海市徐汇区龙吴路 2715 号或银都路 218 号 Life Technologies 北京分公司 地址:北京市朝阳区东三环北路 2 号南银大厦 17 层 Life Technologies 北京生产基地 地址:北京市经济技术开发区荣昌东街 7 号,隆盛工业园 203 Life Technologies 广州办事处

地址:广州市环市东路 371-376 号世界贸易中心大厦南塔 10 层 Life Technologies 广州生产基地: 地址:广州市海珠区新港东路 2492 号海珠科技园 413 室 联系方式: 应聘者请将中文简历邮件发送至: cn.recruit@invitrogen.com 公司名称:美国 INVITROGEN 生命技术公司 公司地址:上海市虹桥路 1 号港汇中心一座 17 层 北京市朝阳区东三环北路 2 号南银大厦 17 层 传真: 公司主页:www.lifetechnologies.com

※ 发布本招聘广告企业的营业执照名称: 爱普拜斯应用生物系统贸易 (上海) 有限公司北京分公司


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